SKOR1 Positive Control for STJ507768 peptide (STJ507770) STJ507770-5 上海玉博生物科技有限公司

SKOR1 Positive Control for STJ507768 peptide (STJ507770)

简单介绍

SKOR1 Positive Control for STJ507768 peptide (STJ507770)

产品描述

Applications:	WB
Note:	STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description:	SKOR1 Positive Control for STJ507768 is synthetically produced from the N-Term sequence and is suitable for use in western blot applications.

Formulation:	Provided as 100 uL ready-to-use, in SDS-PAGE sample buffer (Laemelli's buffer) containing Tris, pH 6.8, 1 % SDS, Glycerol and Bromophenolblue blue as tracking dye. The sample is reduced by adding 2% beta mercaptoethanol. The protein concentration is
Storage Instruction:	Store at-20°C for long term storage. Avoid freeze-thaw cycles.

Gene Symbol:	Htr1a
Gene ID:	24473
Uniprot ID:	5HT1A_RAT
Immunogen Region:	N-Term
Specificity:	This is positive control is recommended for use in combination with SKOR1 antibody STJ507768.
Immunogen:	Synthetic peptide corresponding to amino acids within region 650-700 on human SKOR1 protein.

Function	G-protein coupled receptor for 5-hydroxytryptamine (serotonin). Also functions as a receptor for various drugs and psychoactive substances. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors, such as adenylate cyclase. Beta-arrestin family members inhibit signaling via G proteins and mediate activation of alternative signaling pathways. Signaling inhibits adenylate cyclase activity and activates a phosphatidylinositol-calcium second messenger system that regulates the release of Ca(2+) ions from intracellular stores. Plays a role in the regulation of 5-hydroxytryptamine release and in the regulation of dopamine and 5-hydroxytryptamine metabolism. Plays a role in the regulation of dopamine and 5-hydroxytryptamine levels in the brain, and thereby affects neural activity, mood and behavior. Plays a role in the response to anxiogenic stimuli.
Peptide Name	5-Hydroxytryptamine Receptor 1a 5-Ht-1a 5-Ht1a Serotonin Receptor 1a
Database Links	Reactome: R-RNO-390666
Cellular Localisation	Cell Membrane Multi-Pass Membrane Protein Cell Projection Dendrite
Alternative Peptide Names	5-Hydroxytryptamine Receptor 1a protein 5-Ht-1a protein 5-Ht1a protein Serotonin Receptor 1a protein Htr1a protein 5ht1a protein

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance

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