Human DPP8 (Dipeptidyl Peptidase 8) Sandwich ELISA Kit (STJE0008497) STJE0008497 上海玉博生物科技有限公司

Human DPP8 (Dipeptidyl Peptidase 8) Sandwich ELISA Kit (STJE0008497)

简单介绍

Human DPP8 (Dipeptidyl Peptidase 8) Sandwich ELISA Kit (STJE0008497)

产品描述

Applications:	ELISA
Reactivity:	Human
Note:	STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Sensitivity:	0.117ng/mL
Detection Limit:	0.312-20ng/mL
Short Description:	This DPP8 Sandwich ELISA Kit is an in-vitro enzyme-linked immunosorbent assay for the measurement of samples in human cell culture supernatant, serum and plasma (EDTA, citrate, heparin).

Storage Instruction:	Store the unopened kit in the fridge at 2-8°C for up to 6 months. Once opened store individual kit contents according to components table provided with the kit.
Assay Time:	4.5 hrs

Gene Symbol:	DPP8
Gene ID:	54878
Uniprot ID:	DPP8_HUMAN
Sample Type:	tissue homogenates or other biological fluids.

Tissue Specificity	Ubiquitously expressed, with highest levels in testis, placenta, prostate, muscle and brain.
Post Translational Modifications
Function	Dipeptidyl peptidase that cleaves off N-terminal dipeptides from proteins having a Pro or Ala residue at position 2. Acts as a key inhibitor of caspase-1-dependent monocyte and macrophage pyroptosis in resting cells by preventing activation of NLRP1 and CARD8. Sequesters the cleaved C-terminal part of NLRP1 and CARD8, which respectively constitute the active part of the NLRP1 and CARD8 inflammasomes, in a ternary complex, thereby preventing their oligomerization and activation. The dipeptidyl peptidase activity is required to suppress NLRP1 and CARD8.however, neither NLRP1 nor CARD8 are bona fide substrates of DPP8, suggesting the existence of substrate(s) required for NLRP1 and CARD8 inhibition.
Protein Name	Dipeptidyl Peptidase 8 Dp8 Dipeptidyl Peptidase Iv-Related Protein 1 Dprp-1 Dipeptidyl Peptidase Viii Dpp Viii Prolyl Dipeptidase Dpp8
Database Links
Cellular Localisation	Cytoplasm
Alternative ELISA Names	Dipeptidyl Peptidase 8 ELISA kit Dp8 ELISA kit Dipeptidyl Peptidase Iv-Related Protein 1 ELISA kit Dprp-1 ELISA kit Dipeptidyl Peptidase Viii ELISA kit Dpp Viii ELISA kit Prolyl Dipeptidase Dpp8 ELISA kit DPP8 ELISA kit DPRP1 ELISA kit MSTP097 ELISA kit MSTP135 ELISA kit MSTP141 ELISA kit
output

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance

产品留言

标题

联系人

联系电话

内容

验证码

点击换一张

注：1.可以使用快捷键Alt+S或Ctrl+Enter发送信息!
2.如有必要,请您留下您的详细联系方式!

产品目录