Anti-APOBEC3D/F antibody (232-281 aa) (STJ91636) STJ91636 上海玉博生物科技有限公司

Anti-APOBEC3D/F antibody (232-281 aa) (STJ91636)

如果您对该产品感兴趣的话，可以
产品名称：Anti-APOBEC3D/F antibody (232-281 aa) (STJ91636)
产品型号：STJ91636
产品展商：ST john's laboratory
产品文档：无相关文档

简单介绍

Anti-APOBEC3D/F antibody (232-281 aa) (STJ91636)

产品描述

Host:	Rabbit
Applications:	WB/IHC/IF/ELISA
Reactivity:	Human/Monkey
Note:	STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description:	Rabbit polyclonal antibody anti-DNA dC->dU-editing enzyme APOBEC-3D and DNA dC->dU-editing enzyme APOBEC-3F (232-281 aa) is suitable for use in Western Blot, Immunohistochemistry, Immunofluorescence and ELISA research applications.

Clonality:	Polyclonal
Conjugation:	Unconjugated
Isotype:	IgG
Formulation:	Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide.
Purification:	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration:	1 mg/mL
Dilution Range:	WB 1:500-1:2000 IHC 1:100-1:300 ELISA 1:40000 IF 1:50-200
Storage Instruction:	Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.

Gene Symbol:	APOBEC3F APOBEC3D
Gene ID:	200316 NA
Uniprot ID:	ABC3F_HUMAN ABC3D_HUMAN
Immunogen Region:	232-281 aa
Specificity:	APOBEC3D/F Polyclonal Antibody detects endogenous levels of APOBEC3D/F protein.
Immunogen:	The antiserum was produced against synthesized peptide derived from the human APOBEC3D/F at the amino acid range 232-281

Function	DNA deaminase (cytidine deaminase) which acts as an inhibitor of retrovirus replication and retrotransposon mobility via deaminase-dependent and -independent mechanisms. Exhibits antiviral activity against Vif-deficient HIV-1. After the penetration of retroviral nucleocapsids into target cells of infection and the initiation of reverse transcription, it can induce the conversion of cytosine to uracil in the minus-sense single-strand viral DNA, leading to G-to-A hypermutations in the subsequent plus-strand viral DNA. The resultant detrimental levels of mutations in the proviral genome, along with a deamination-independent mechanism that works prior to the proviral integration, together exert efficient antiretroviral effects in infected target cells. Selectively targets single-stranded DNA and does not deaminate double-stranded DNA or single- or double-stranded RNA. Exhibits antiviral activity also against hepatitis B virus (HBV), equine infectious anemia virus (EIAV), xenotropic MuLV-related virus (XMRV) and simian foamy virus (SFV) and may inhibit the mobility of LTR and non-LTR retrotransposons. May also play a role in the epigenetic regulation of gene expression through the process of active DNA demethylation.
Protein Name	Dna Dc->Du-Editing Enzyme Apobec-3f Apolipoprotein B Mrna-Editing Enzyme Catalytic Polypeptide-Like 3f A3f
Cellular Localisation	Cytoplasm P-Body
Alternative Antibody Names	Anti-Dna Dc->Du-Editing Enzyme Apobec-3f antibody Anti-Apolipoprotein B Mrna-Editing Enzyme Catalytic Polypeptide-Like 3f antibody Anti-A3f antibody Anti-APOBEC3F antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance

产品留言

标题

联系人

联系电话

内容

验证码

点击换一张

注：1.可以使用快捷键Alt+S或Ctrl+Enter发送信息!
2.如有必要,请您留下您的详细联系方式!

温馨提示：为规避购买风险，建议您在购买前务必确认供应商资质与产品质量。
免责申明：以上内容为注册会员自行发布，若信息的真实性、合法性存在争议，平台将会监督协助处理，欢迎举报

产品目录

产品资料

Anti-APOBEC3D/F antibody (232-281 aa) (STJ91636)