Anti-APOBEC3F antibody (189-373) (STJ119417) STJ119417 上海玉博生物科技有限公司

Anti-APOBEC3F antibody (189-373) (STJ119417)

如果您对该产品感兴趣的话，可以
产品名称：Anti-APOBEC3F antibody (189-373) (STJ119417)
产品型号：STJ119417
产品展商：ST john's laboratory
产品文档：无相关文档

简单介绍

Anti-APOBEC3F antibody (189-373) (STJ119417)

产品描述

Host:	Rabbit
Applications:	WB
Reactivity:	Human
Note:	STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description:	Rabbit polyclonal antibody anti-APOBEC3F (189-373) is suitable for use in Western Blot research applications.

Clonality:	Polyclonal
Conjugation:	Unconjugated
Isotype:	IgG
Formulation:	PBS with 0.02% Sodium Azide, 50% Glycerol, pH7.3.
Purification:	Affinity purification
Dilution Range:	WB 1:500-1:2000
Storage Instruction:	Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.

Gene Symbol:	APOBEC3F
Gene ID:	200316
Uniprot ID:	ABC3F_HUMAN
Immunogen Region:	189-373
Immunogen:	Recombinant fusion protein containing a sequence corresponding to amino acids 189-373 of human APOBEC3F (NP_660341.2).
Immunogen Sequence:	RNPMEAMYPHIFYFHFKNLR KAYGRNESWLCFTMEVVKHH SPVSWKRGVFRNQVDPETHC HAERCFLSWFCDDILSPNTN YEVTWYTSWSPCPECAGEVA EFLARHSNVNLTIFTARLYY FWDTDYQEGLRSLSQEGASV EIMGYKDFKYCWENFVYNDD EPFKPWKGLKYNFLFLDSKL QEILE

Tissue Specificity	Widely expressed. Highly expressed in ovary.
Function	DNA deaminase (cytidine deaminase) which acts as an inhibitor of retrovirus replication and retrotransposon mobility via deaminase-dependent and -independent mechanisms. Exhibits antiviral activity against viruse such as HIV-1 or HIV-2. After the penetration of retroviral nucleocapsids into target cells of infection and the initiation of reverse transcription, it can induce the conversion of cytosine to uracil in the minus-sense single-strand viral DNA, leading to G-to-A hypermutations in the subsequent plus-strand viral DNA. The resultant detrimental levels of mutations in the proviral genome, along with a deamination-independent mechanism that works prior to the proviral integration, together exert efficient antiretroviral effects in infected target cells. Selectively targets single-stranded DNA and does not deaminate double-stranded DNA or single- or double-stranded RNA. Exhibits antiviral activity also against hepatitis B virus (HBV), equine infectious anemia virus (EIAV), xenotropic MuLV-related virus (XMRV) and simian foamy virus (SFV) and may inhibit the mobility of LTR and non-LTR retrotransposons. May also play a role in the epigenetic regulation of gene expression through the process of active DNA demethylation.
Protein Name	Dna Dc->Du-Editing Enzyme Apobec-3f Apolipoprotein B Mrna-Editing Enzyme Catalytic Polypeptide-Like 3f A3f
Cellular Localisation	Cytoplasm P-Body
Alternative Antibody Names	Anti-Dna Dc->Du-Editing Enzyme Apobec-3f antibody Anti-Apolipoprotein B Mrna-Editing Enzyme Catalytic Polypeptide-Like 3f antibody Anti-A3f antibody Anti-APOBEC3F antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance

产品留言

标题

联系人

联系电话

内容

验证码

点击换一张

注：1.可以使用快捷键Alt+S或Ctrl+Enter发送信息!
2.如有必要,请您留下您的详细联系方式!

温馨提示：为规避购买风险，建议您在购买前务必确认供应商资质与产品质量。
免责申明：以上内容为注册会员自行发布，若信息的真实性、合法性存在争议，平台将会监督协助处理，欢迎举报

产品目录

产品资料

Anti-APOBEC3F antibody (189-373) (STJ119417)