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Human DUSP6 (Dual Specificity Phosphatase 6) Sandwich ELISA Kit (STJE0008534)

Human DUSP6 (Dual Specificity Phosphatase 6) Sandwich ELISA Kit (STJE0008534)
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  • 产品名称:Human DUSP6 (Dual Specificity Phosphatase 6) Sandwich ELISA Kit (STJE0008534)
  • 产品型号:STJE0008534
  • 产品展商:ST john's laboratory
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简单介绍
Human DUSP6 (Dual Specificity Phosphatase 6) Sandwich ELISA Kit (STJE0008534)
产品描述
Applications: ELISA
Reactivity: Human
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Sensitivity: 0.122ng/mL
Detection Limit: 0.312-20ng/mL
Short Description: This DUSP6 Sandwich ELISA Kit is an in-vitro enzyme-linked immunosorbent assay for the measurement of samples in human cell culture supernatant, serum and plasma (EDTA, citrate, heparin).
Storage Instruction: Store the unopened kit in the fridge at 2-8°C for up to 6 months. Once opened store individual kit contents according to components table provided with the kit.
Assay Time: 4.5 hrs
Gene Symbol: DUSP6
Gene ID: 1848
Uniprot ID: DUS6_HUMAN
Sample Type: tissue homogenates, cell lysates or other biological fluids.
Tissue Specificity Expressed in keratinocytes (at protein level).
Post Translational Modifications
Function Inactivates MAP kinases. Has a specificity for the ERK family. Plays an important role in alleviating chronic postoperative pain. Necessary for the normal dephosphorylation of the long-lasting phosphorylated forms of spinal MAPK1/3 and MAP kinase p38 induced by peripheral surgery, which drives the resolution of acute postoperative allodynia. Also important for dephosphorylation of MAPK1/3 in local wound tissue, which further contributes to resolution of acute pain. Promotes cell differentiation by regulating MAPK1/MAPK3 activity and regulating the expression of AP1 transcription factors.
Protein Name Dual Specificity Protein Phosphatase 6
Dual Specificity Protein Phosphatase Pyst1
Mitogen-Activated Protein Kinase Phosphatase 3
Map Kinase Phosphatase 3
Mkp-3
Database Links Reactome: R-HSA-112409
Reactome: R-HSA-202670
Reactome: R-HSA-5675221
Reactome: R-HSA-9652817
Cellular Localisation Cytoplasm
Alternative ELISA Names Dual Specificity Protein Phosphatase 6 ELISA kit
Dual Specificity Protein Phosphatase Pyst1 ELISA kit
Mitogen-Activated Protein Kinase Phosphatase 3 ELISA kit
Map Kinase Phosphatase 3 ELISA kit
Mkp-3 ELISA kit
DUSP6 ELISA kit
MKP3 ELISA kit
PYST1 ELISA kit
output

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
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