Anti-Bak1 antibody (50-150) (STJ22759) STJ22759 上海玉博生物科技有限公司

Anti-Bak1 antibody (50-150) (STJ22759)

简单介绍

Anti-Bak1 antibody (50-150) (STJ22759)

产品描述

Host:	Rabbit
Applications:	WB/IF/IP
Reactivity:	Human/Mouse/Rat
Note:	STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description:	Rabbit polyclonal antibody anti-Bak (50-150) is suitable for use in Western Blot, Immunofluorescence and Immunoprecipitation research applications.

Clonality:	Polyclonal
Conjugation:	Unconjugated
Isotype:	IgG
Formulation:	PBS with 0.01% Thimerosal, 50% Glycerol, pH7.3.
Purification:	Affinity purification
Dilution Range:	WB 1:500-1:1000 IF/ICC 1:50-1:200 IP 1:500-1:1000
Storage Instruction:	Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.

Gene Symbol:	BAK1
Gene ID:	578
Uniprot ID:	BAK_HUMAN
Immunogen Region:	50-150
Immunogen:	A synthetic peptide corresponding to a sequence within amino acids 50-150 of human Bak (NP_001179.1).
Immunogen Sequence:	EGVAAPADPEMVTLPLQPSS TMGQVGRQLAIIGDDINRRY DSEFQTMLQHLQPTAENAYE YFTKIATSLFESGINWGRVV ALLGFGYRLALHVYQHGLTG F

Tissue Specificity	Expressed in a wide variety of tissues, with highest levels in the heart and skeletal muscle.
Function	Plays a role in the mitochondrial apoptotic process. Upon arrival of cell death signals, promotes mitochondrial outer membrane (MOM) permeabilization by oligomerizing to form pores within the MOM. This releases apoptogenic factors into the cytosol, including cytochrome c, promoting the activation of caspase 9 which in turn processes and activates the effector caspases.
Protein Name	Bcl-2 Homologous Antagonist/Killer Apoptosis Regulator Bak Bcl-2-Like Protein 7 Bcl2-L-7
Database Links	Reactome: R-HSA-111452 Reactome: R-HSA-111457 Reactome: R-HSA-5620971
Cellular Localisation	Mitochondrion Outer Membrane Single-Pass Membrane Protein
Alternative Antibody Names	Anti-Bcl-2 Homologous Antagonist/Killer antibody Anti-Apoptosis Regulator Bak antibody Anti-Bcl-2-Like Protein 7 antibody Anti-Bcl2-L-7 antibody Anti-BAK1 antibody Anti-BAK antibody Anti-BCL2L7 antibody Anti-CDN1 antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance

产品留言

标题

联系人

联系电话

内容

验证码

点击换一张

注：1.可以使用快捷键Alt+S或Ctrl+Enter发送信息!
2.如有必要,请您留下您的详细联系方式!

产品目录