Anti-BANP antibody (1-260) (STJ29732) STJ29732 上海玉博生物科技有限公司

Anti-BANP antibody (1-260) (STJ29732)

简单介绍

Anti-BANP antibody (1-260) (STJ29732)

产品描述

Host:	Rabbit
Applications:	WB
Reactivity:	Human/Mouse
Note:	STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description:	Rabbit polyclonal antibody anti-BANP (1-260) is suitable for use in Western Blot research applications.

Clonality:	Polyclonal
Conjugation:	Unconjugated
Isotype:	IgG
Formulation:	PBS with 0.02% Sodium Azide, 50% Glycerol, pH7.3.
Purification:	Affinity purification
Dilution Range:	WB 1:500-1:2000
Storage Instruction:	Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.

Gene Symbol:	BANP
Gene ID:	54971
Uniprot ID:	BANP_HUMAN
Immunogen Region:	1-260
Immunogen:	Recombinant fusion protein containing a sequence corresponding to amino acids 1-260 of human BANP (NP_060339.2).
Immunogen Sequence:	MMSEHDLADVVQIAVEDLSP DHPVVLENHVVTDEDEPALK RQRLEINCQDPSIKSFLYSI NQTICLRLDSIEAKLQALEA TCKSLEEKLDLVTNKQHSPI QVPMVAGSPLGATQTCNKVR CAVPGRRQNTIVVKVPGQED SHHEDGESGSEASDSVSSCG QAGSQSIGSNVTLITLNSEE DYPNGTWLGDENNPEMRVRC AIIPSDMLHISTNCRTAEKM ALTLLDYLFHREVQAVSNL

Tissue Specificity	Down-regulated in breast cancer cell lines.
Function	Controls V(D)J recombination during T-cell development by repressing T-cell receptor (TCR) beta enhancer function. Binds to scaffold/matrix attachment region beta (S/MARbeta), an ATC-rich DNA sequence located upstream of the TCR beta enhancer. Represses cyclin D1 transcription by recruiting HDAC1 to its promoter, thereby diminishing H3K9ac, H3S10ph and H4K8ac levels. Promotes TP53 activation, which causes cell cycle arrest.
Protein Name	Protein Banp Ben Domain-Containing Protein 1 Btg3-Associated Nuclear Protein Scaffold/Matrix-Associated Region-1-Binding Protein
Database Links	Reactome: R-HSA-6804759
Cellular Localisation	Nucleus
Alternative Antibody Names	Anti-Protein Banp antibody Anti-Ben Domain-Containing Protein 1 antibody Anti-Btg3-Associated Nuclear Protein antibody Anti-Scaffold/Matrix-Associated Region-1-Binding Protein antibody Anti-BANP antibody Anti-BEND1 antibody Anti-SMAR1 antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance

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