Human EFEMP2 (EGF-containing fibulin-like extracellular matrix protein 2) CLIA Kit (STJC0000224) STJC0000224 上海玉博生物科技有限公司

Human EFEMP2 (EGF-containing fibulin-like extracellular matrix protein 2) CLIA Kit (STJC0000224)

如果您对该产品感兴趣的话，可以
产品名称：Human EFEMP2 (EGF-containing fibulin-like extracellular matrix protein 2) CLIA Kit (STJC0000224)
产品型号：STJC0000224
产品展商：ST john's laboratory
产品文档：无相关文档

简单介绍

Human EFEMP2 (EGF-containing fibulin-like extracellular matrix protein 2) CLIA Kit (STJC0000224)

产品描述

Applications:	CLIA
Reactivity:	Human
Note:	FOR SCIENTIFIC EDUCATIONAL RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR OTHER MEDICAL APPLICATIONS.
Sensitivity:	0.38ng/mL
Detection Limit:	0.63~40ng/mL
Short Description:	This human EFEMP2 kit is a highly sensitive in-vitro chemiluminescent immunoassay for the measurement of trace amounts of analytes.

Storage Instruction:	If unopened the kit may be stored at 2-8°C for up to 1 month. If the kit will not be used within 1 month, store the components separately, according to the component table in the manual.
Assay Time:	3.5h
Detection:	Chemiluminescence

Gene Symbol:	EFEMP2
Gene ID:	30008
Uniprot ID:	FBLN4_HUMAN
Specificity:	This kit recognizes Human FBLN4 in samples. No significant cross-reactivity or interference between Human FBLN4 and analogues was observed.
Sample Type:	Serum, plasma and other biological fluids

Post Translational Modifications	N-glycosylated.contains mostly complex-type glycans. Not O-glycosylated. Cleaved by ELANE.produces a 50-55 kDa fragment. Cleaved by MMP2 and MMP9.produces several fragments.
Function	Plays a crucial role in elastic fiber formation in tissue, and in the formation of ultrastructural connections between elastic laminae and smooth muscle cells in the aorta, therefore participates in terminal differentiation and maturation of smooth muscle cell (SMC) and in the mechanical properties and wall integrity maintenance of the aorta. In addition, is involved in the control of collagen fibril assembly in tissue throught proteolytic activation of LOX leading to cross- linking of collagen and elastin. Also promotes ELN coacervation and participates in the deposition of ELN coacervates on to microfibrils but also regulates ELN cross- linking through LOX interaction. Moreover adheres to the cells through heparin binding in a calcium-dependent manner and regulates vascularlar smooth muscle cells proliferation through angiotensin signaling.
Protein Name	Egf-Containing Fibulin-Like Extracellular Matrix Protein 2 Fibulin-4 Fibl-4 Protein Uph1
Database Links	Reactome: R-HSA-2129379
Cellular Localisation	Secreted Extracellular Space Extracellular Matrix Basement Membrane Localizes On The Microfibrils Surrounding Eln Cores
Alternative CLIA Names	Egf-Containing Fibulin-Like Extracellular Matrix Protein 2 CLIA kit Fibulin-4 CLIA kit Fibl-4 CLIA kit Protein Uph1 CLIA kit EFEMP2 CLIA kit FBLN4 CLIA kit UNQ200 CLIA kit PRO226 CLIA kit
Specificity	This kit recognizes Human FBLN4 in samples. No significant cross-reactivity or interference between Human FBLN4 and analogues was observed.
Reproducibility	Both intra-CV and inter-CV are

Information sourced from Uniprot.org

Item Specifications Storage

Micro CLIA Plate (Dismountable)	96T: 8 wells ×12 strips strips	-20℃, 6 months
Reference Standard	96T: 2 vials 48T: 1 vial	-20℃, 6 months
Concentrated Biotinylated Detection Ab (100×)	96T: 1 vial, 120 μL 60 μL	-20℃, 6 months
Concentrated HRP Conjugate (100×)	96T: 1 vial, 120 μL 60 μL	-20℃ (Protect from light), 6 months
Reference Standard & Sample Diluent	1 vial, 20 mL	2-8°C, 6 months
Biotinylated Detection Ab Diluent	1 vial, 14 mL	2-8°C, 6 months
HRP Conjugate Diluent	1 vial, 14 mL	2-8°C, 6 months
Concentrated Wash Buffer (25×)	1 vial, 30 mL	2-8°C, 6 months
Substrate Reagent A	1 vial, 5 mL	2-8℃ (Protect from light)
Substrate Reagent B	1 vial, 5 mL	2-8℃ (Protect from light)
Plate Sealer	5 pieces
Manual	1 copy
Certificate of Analysis	1 copy

Sample Type Range (%) Average Recovery (%)

Serum(n=8)	91-104	98
EDTA plasma(n=8)	88-100	94
Cell culture media(n=8)	90-103	97

Intra-assay Precision Intra-assay Precision Intra-assay Precision Inter-assay Precision Inter-assay Precision Inter-assay Precision

Sample	1.00	2.00	3.00	1.00	2.00	3.00
n	20.00	20.00	20.00	20.00	20.00	20.00
Mean (ng/mL)	1.85	5.34	16.51	2.03	5.72	16.91
Standard deviation	0.19	0.62	1.45	0.24	0.47	1.94
CV (%)	10.27	11.61	8.78	11.82	8.22	11.47

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance

产品留言

标题

联系人

联系电话

内容

验证码

点击换一张

注：1.可以使用快捷键Alt+S或Ctrl+Enter发送信息!
2.如有必要,请您留下您的详细联系方式!

温馨提示：为规避购买风险，建议您在购买前务必确认供应商资质与产品质量。
免责申明：以上内容为注册会员自行发布，若信息的真实性、合法性存在争议，平台将会监督协助处理，欢迎举报

产品目录

产品资料

Human EFEMP2 (EGF-containing fibulin-like extracellular matrix protein 2) CLIA Kit (STJC0000224)