Human EFNB2 (Ephrin B2) Sandwich ELISA Kit (STJE0008587) STJE0008587 上海玉博生物科技有限公司

Human EFNB2 (Ephrin B2) Sandwich ELISA Kit (STJE0008587)

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产品名称：Human EFNB2 (Ephrin B2) Sandwich ELISA Kit (STJE0008587)
产品型号：STJE0008587
产品展商：ST john's laboratory
产品文档：无相关文档

简单介绍

Human EFNB2 (Ephrin B2) Sandwich ELISA Kit (STJE0008587)

产品描述

Applications:	ELISA
Reactivity:	Human
Note:	STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Sensitivity:	0.053ng/mL
Detection Limit:	0.156-10ng/mL
Short Description:	This EFNB2 Sandwich ELISA Kit is an in-vitro enzyme-linked immunosorbent assay for the measurement of samples in human cell culture supernatant, serum and plasma (EDTA, citrate, heparin).

Storage Instruction:	Store the unopened kit in the fridge at 2-8°C for up to 6 months. Once opened store individual kit contents according to components table provided with the kit.
Assay Time:	4.5 hrs

Gene Symbol:	EFNB2
Gene ID:	1948
Uniprot ID:	EFNB2_HUMAN
Sample Type:	tissue homogenates, cell lysates or other biological fluids.

Tissue Specificity	Lung and kidney.
Post Translational Modifications	Inducible phosphorylation of tyrosine residues in the cytoplasmic domain.
Function	Cell surface transmembrane ligand for Eph receptors, a family of receptor tyrosine kinases which are crucial for migration, repulsion and adhesion during neuronal, vascular and epithelial development. Binds promiscuously Eph receptors residing on adjacent cells, leading to contact-dependent bidirectional signaling into neighboring cells. The signaling pathway downstream of the receptor is referred to as forward signaling while the signaling pathway downstream of the ephrin ligand is referred to as reverse signaling. Binds to receptor tyrosine kinase including EPHA4, EPHA3 and EPHB4. Together with EPHB4 plays a central role in heart morphogenesis and angiogenesis through regulation of cell adhesion and cell migration. EPHB4-mediated forward signaling controls cellular repulsion and segregation from EFNB2-expressing cells. May play a role in constraining the orientation of longitudinally projecting axons. (Microbial infection) Acts as a receptor for Hendra virus and Nipah virus.
Protein Name	Ephrin-B2 Eph-Related Receptor Tyrosine Kinase Ligand 5 Lerk-5 Htk Ligand Htk-L
Database Links	Reactome: R-HSA-2682334 Reactome: R-HSA-3928662 Reactome: R-HSA-3928664 Reactome: R-HSA-3928665
Cellular Localisation	Cell Membrane Single-Pass Type I Membrane Protein Cell Junction Adherens Junction
Alternative ELISA Names	Ephrin-B2 ELISA kit Eph-Related Receptor Tyrosine Kinase Ligand 5 ELISA kit Lerk-5 ELISA kit Htk Ligand ELISA kit Htk-L ELISA kit EFNB2 ELISA kit EPLG5 ELISA kit HTKL ELISA kit LERK5 ELISA kit
output

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance

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Human EFNB2 (Ephrin B2) Sandwich ELISA Kit (STJE0008587)