Anti-BCDIN3D antibody (1-292) (STJ119854) STJ119854 上海玉博生物科技有限公司

Anti-BCDIN3D antibody (1-292) (STJ119854)

简单介绍

Anti-BCDIN3D antibody (1-292) (STJ119854)

产品描述

Host:	Rabbit
Applications:	WB
Reactivity:	Human/Mouse
Note:	STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description:	Rabbit polyclonal antibody anti-BCDIN3D (1-292) is suitable for use in Western Blot research applications.

Clonality:	Polyclonal
Conjugation:	Unconjugated
Isotype:	IgG
Formulation:	PBS with 0.01% Thimerosal, 50% Glycerol, pH7.3.
Purification:	Affinity purification
Dilution Range:	WB 1:500-1:2000
Storage Instruction:	Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.

Gene Symbol:	BCDIN3D
Gene ID:	144233
Uniprot ID:	BN3D2_HUMAN
Immunogen Region:	1-292
Immunogen:	Recombinant fusion protein containing a sequence corresponding to amino acids 1-292 of human BCDIN3D (NP_859059.1).
Immunogen Sequence:	MAVPTELDGGSVKETAAEEE SRVLAPGAAPFGNFPHYSRF HPPEQRLRLLPPELLRQLFP ESPENGPILGLDVGCNSGDL SVALYKHFLSLPDGETCSDA SREFRLLCCDIDPVLVKRAE KECPFPDALTFITLDFMNQR TRKVLLSSFLSQFGRSVFDI GFCMSITMWIHLNHGDHGLW EFLAHLSSLCHYLLVEPQPW KCYRAAARRLRKLGLHDFDH FHSLAIRGDMPNQIVQILT

Function	O-methyltransferase that specifically monomethylates 5'-monophosphate of cytoplasmic histidyl tRNA (tRNA(His)), acting as a capping enzyme by protecting tRNA(His) from cleavage by DICER1. Also able, with less efficiently, to methylate the 5' monophosphate of a subset of pre-miRNAs, acting as a negative regulator of miRNA processing. The 5' monophosphate of pre-miRNAs is recognized by DICER1 and is required for pre-miRNAs processing: methylation at this position reduces the processing of pre-miRNAs by DICER1. Was also reported to mediate dimethylation of pre-miR-145.however dimethylation cannot be reproduced by another group which observes a monomethylation of pre-miR-145.
Protein Name	Rna 5'-Monophosphate Methyltransferase Bcdin3 Domain-Containing Protein
Database Links	Reactome: R-HSA-203927
Cellular Localisation	Cytoplasm
Alternative Antibody Names	Anti-Rna 5'-Monophosphate Methyltransferase antibody Anti-Bcdin3 Domain-Containing Protein antibody Anti-BCDIN3D antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance

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