Anti-BCHE antibody (29-270) (STJ22770) STJ22770 上海玉博生物科技有限公司

Anti-BCHE antibody (29-270) (STJ22770)

简单介绍

Anti-BCHE antibody (29-270) (STJ22770)

产品描述

Host:	Rabbit
Applications:	WB
Reactivity:	Human/Mouse/Rat
Note:	STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description:	Rabbit polyclonal antibody anti-BCHE (29-270) is suitable for use in Western Blot research applications.

Clonality:	Polyclonal
Conjugation:	Unconjugated
Isotype:	IgG
Formulation:	PBS with 0.02% Sodium Azide, 50% Glycerol, pH7.3.
Purification:	Affinity purification
Dilution Range:	WB 1:500-1:2000
Storage Instruction:	Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.

Gene Symbol:	BCHE
Gene ID:	590
Uniprot ID:	CHLE_HUMAN
Immunogen Region:	29-270
Immunogen:	Recombinant fusion protein containing a sequence corresponding to amino acids 29-270 of human Butyrylcholinesterase (NP_000046.1).
Immunogen Sequence:	EDDIIIATKNGKVRGMNLTV FGGTVTAFLGIPYAQPPLGR LRFKKPQSLTKWSDIWNATK YANSCCQNIDQSFPGFHGSE MWNPNTDLSEDCLYLNVWIP APKPKNATVLIWIYGGGFQT GTSSLHVYDGKFLARVERVI VVSMNYRVGALGFLALPGNP EAPGNMGLFDQQLALQWVQK NIAAFGGNPKSVTLFGESAG AASVSLHLLSPGSHSLFTRA ILQSGSFNAPWAVTSLYEA

Tissue Specificity	Detected in blood plasma (at protein level). Present in most cells except erythrocytes.
Post Translational Modifications	N-glycosylated. No other PTM detected. The major N-glycan structures are of the complex diantennary type with 1 and 2 N-acetylneuraminic acid molecules (Neu5Ac) making up approximately 33% and 47% of the total N-glycans, respectively. Only low amounts of fucosylated diantennary N-glycans are detected (approximately 2%). Triantennary N-glycans with or without fucose amount to approximately 13%, whereas 5% of the total N-glycans are of the oligomannosidic or hybrid type.
Function	Esterase with broad substrate specificity. Contributes to the inactivation of the neurotransmitter acetylcholine. Can degrade neurotoxic organophosphate esters.
Protein Name	Cholinesterase Acylcholine Acylhydrolase Butyrylcholine Esterase Choline Esterase Ii Pseudocholinesterase
Database Links	Reactome: R-HSA-112311 Reactome: R-HSA-1483191 Reactome: R-HSA-422085 Reactome: R-HSA-9749641
Cellular Localisation	Secreted
Alternative Antibody Names	Anti-Cholinesterase antibody Anti-Acylcholine Acylhydrolase antibody Anti-Butyrylcholine Esterase antibody Anti-Choline Esterase Ii antibody Anti-Pseudocholinesterase antibody Anti-BCHE antibody Anti-CHE1 antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance

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