Anti-AQP2 antibody (200-250) (STJ500126) STJ500126-100 上海玉博生物科技有限公司

Anti-AQP2 antibody (200-250) (STJ500126)

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产品名称：Anti-AQP2 antibody (200-250) (STJ500126)
产品型号：STJ500126-100
产品展商：ST john's laboratory
产品文档：无相关文档

简单介绍

Anti-AQP2 antibody (200-250) (STJ500126)

产品描述

Host:	Rabbit
Applications:	ELISA/IP/WB
Reactivity:	Bovine/Human/Mouse/Rat/Sheep
Note:	STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description:	Rabbit polyclonal antibody anti-AQP2 (200-250) is suitable for use in ELISA, Immunoprecipitation and Western Blot research applications.

Clonality:	Polyclonal
Conjugation:	Unconjugated
Isotype:	IgG
Purification:	Affinity Purified
Concentration:	0.50-0.62 µg/µl
Dilution Range:	WB: 1:500 ELISA: 1:10, 000 IP: 1:200
Storage Instruction:	Store at-20°C for long term storage. Avoid freeze-thaw cycles.

Gene Symbol:	Aqp2
Gene ID:	25386
Uniprot ID:	AQP2_RAT
Immunogen Region:	200-250
Immunogen:	Synthetic peptide taken within amino acid region 200-250 on human Aquaporin 2 protein.

Tissue Specificity	Detected in kidney, in cortical and the medullary collecting tubules (at protein level). Detected in kidney medulla and cortex.
Post Translational Modifications	Ser-256 phosphorylation is necessary and sufficient for expression at the apical membrane. Endocytosis is not phosphorylation-dependent. N-glycosylated.
Function	Forms a water-specific channel that provides the plasma membranes of renal collecting duct with high permeability to water, thereby permitting water to move in the direction of an osmotic gradient. Plays an essential role in renal water homeostasis.
Protein Name	Aquaporin-2 Aqp-2 Adh Water Channel Aquaporin-Cd Aqp-Cd Collecting Duct Water Channel Protein Wch-Cd Water Channel Protein For Renal Collecting Duct
Database Links	Reactome: R-RNO-432040 Reactome: -RNO-432047
Cellular Localisation	Apical Cell Membrane Multi-Pass Membrane Protein Basolateral Cell Membrane Cell Membrane Cytoplasmic Vesicle Membrane Golgi Apparatus Trans-Golgi Network Membrane Shuttles From Vesicles To The Apical Membrane Vasopressin-Regulated Phosphorylation Is Required For Translocation To The Apical Cell Membrane Plekha8/Fapp2 Is Required To Transport Aqp2 From The Tgn To Sites Where Aqp2 Is Phosphorylated
Alternative Antibody Names	Anti-Aquaporin-2 antibody Anti-Aqp-2 antibody Anti-Adh Water Channel antibody Anti-Aquaporin-Cd antibody Anti-Aqp-Cd antibody Anti-Collecting Duct Water Channel Protein antibody Anti-Wch-Cd antibody Anti-Water Channel Protein For Renal Collecting Duct antibody Anti-Aqp2 antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance

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Anti-AQP2 antibody (200-250) (STJ500126)