Human Galectin-1/LGALS1 protein (Recombinant) (No tag) (STJP000780) STJP000780 上海玉博生物科技有限公司

Human Galectin-1/LGALS1 protein (Recombinant) (No tag) (STJP000780)

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产品名称：Human Galectin-1/LGALS1 protein (Recombinant) (No tag) (STJP000780)
产品型号：STJP000780
产品展商：ST john's laboratory
产品文档：无相关文档

简单介绍

Human Galectin-1/LGALS1 protein (Recombinant) (No tag) (STJP000780)

产品描述

Host:	E. coli
Reactivity:	Human
Note:	STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description:	Recombinant-Human Galectin-1/LGALS1-No tag protein was developed from e. coli and has a target region of No tag. For use in research applications.

Formulation:	Lyophilized from a 0.22 Mu m filtered solution of PBS, pH 7.4. Contact us for customized product form or formulation.
Immunoreactivity:	Measured by its ability to agglutinate mouse red blood cells. The ED50 for this effect is 0.5-3 Mu g/mL.

Gene Symbol:	LGALS1
Gene ID:	3956
Uniprot ID:	LEG1_HUMAN
Immunogen:	Recombinant Human Galectin-1/LGALS1 Protein is produced by E. coli expression system. The target protein is expressed with sequence (Ala2-Asp135) of human Galectin-1 (Accession #NP_002296.1).

Tissue Specificity	Expressed in placenta, maternal decidua and fetal membranes. Within placenta, expressed in trophoblasts, stromal cells, villous endothelium, syncytiotrophoblast apical membrane and villous stroma. Within fetal membranes, expressed in amnion, chorioamniotic mesenchyma and chorion (at protein level). Expressed in cardiac, smooth, and skeletal muscle, neurons, thymus, kidney and hematopoietic cells.
Function	Lectin that binds beta-galactoside and a wide array of complex carbohydrates. Plays a role in regulating apoptosis, cell proliferation and cell differentiation. Inhibits CD45 protein phosphatase activity and therefore the dephosphorylation of Lyn kinase. Strong inducer of T-cell apoptosis.
Protein Name	Galectin-1 Gal-1 14 Kda Laminin-Binding Protein Hlbp14 14 Kda Lectin Beta-Galactoside-Binding Lectin L-14-I Galaptin Hbl Hpl Lactose-Binding Lectin 1 Lectin Galactoside-Binding Soluble 1 Putative Mapk-Activating Protein Pm12 S-Lac Lectin 1
Database Links	Reactome: R-HSA-381426 Reactome: R-HSA-8957275
Cellular Localisation	Secreted Extracellular Space Extracellular Matrix Cytoplasm Can Be Secreted The Secretion Is Dependent On Protein Unfolding And Facilitated By The Cargo Receptor Tmed10 It Results In Protein Translocation From The Cytoplasm Into The Ergic (Endoplasmic Reticulum-Golgi Intermediate Compartment) Followed By Vesicle Entry And Secretion
Alternative Protein Names	Galectin-1 protein Gal-1 protein 14 Kda Laminin-Binding Protein protein Hlbp14 protein 14 Kda Lectin protein Beta-Galactoside-Binding Lectin L-14-I protein Galaptin protein Hbl protein Hpl protein Lactose-Binding Lectin 1 protein Lectin Galactoside-Binding Soluble 1 protein Putative Mapk-Activating Protein Pm12 protein S-Lac Lectin 1 protein LGALS1 protein

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance

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Human Galectin-1/LGALS1 protein (Recombinant) (No tag) (STJP000780)