Anti-ADCY3 antibody (1-80) (STJ110180) STJ110180 上海玉博生物科技有限公司

Anti-ADCY3 antibody (1-80) (STJ110180)

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产品名称：Anti-ADCY3 antibody (1-80) (STJ110180)
产品型号：STJ110180
产品展商：ST john's laboratory
产品文档：无相关文档

简单介绍

Anti-ADCY3 antibody (1-80) (STJ110180)

产品描述

Host:	Rabbit
Applications:	WB
Reactivity:	Human/Mouse
Note:	STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description:	Rabbit polyclonal antibody anti-ADCY3 (1-80) is suitable for use in Western Blot research applications.

Clonality:	Polyclonal
Conjugation:	Unconjugated
Isotype:	IgG
Formulation:	PBS with 0.02% Sodium Azide, 50% Glycerol, pH7.3.
Purification:	Affinity purification
Dilution Range:	WB 1:500-1:1000
Storage Instruction:	Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.

Gene Symbol:	ADCY3
Gene ID:	109
Uniprot ID:	ADCY3_HUMAN
Immunogen Region:	1-80
Immunogen:	Recombinant fusion protein containing a sequence corresponding to amino acids 1-80 of human ADCY3 (NP_004027.2).
Immunogen Sequence:	MPRNQGFSEPEYSAEYSAEY SVSLPSDPDRGVGRTHEISV RNSGSCLCLPRFMRLTFVPE SLENLYQTYFKRQRHETLLV

Tissue Specificity	Detected in zona glomerulosa and zona fasciculata in the adrenal gland (at protein level). Expressed in brain, heart, kidney, liver, lung, pancreas islets, placenta, and skeletal muscle. Detected in testis.
Post Translational Modifications	Sumoylated. Sumoylation is required for targeting ot olfactory cilia. N-glycosylated. Rapidly phosphorylated after stimulation by odorants or forskolin. Phosphorylation by CaMK2 at Ser-1076 down-regulates enzyme activity.
Function	Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. Participates in signaling cascades triggered by odorant receptors via its function in cAMP biosynthesis. Required for the perception of odorants. Required for normal sperm motility and normal male fertility. Plays a role in regulating insulin levels and body fat accumulation in response to a high fat diet.
Protein Name	Adenylate Cyclase Type 3 Atp Pyrophosphate-Lyase 3 Adenylate Cyclase Type Iii Ac-Iii Adenylate Cyclase - Olfactive Type Adenylyl Cyclase 3 Ac3
Database Links	Reactome: R-HSA-163359 Reactome: R-HSA-163615 Reactome: R-HSA-164378 Reactome: R-HSA-170660 Reactome: R-HSA-170670 Reactome: R-HSA-381753 Reactome: R-HSA-418555 Reactome: R-HSA-418594 Reactome: R-HSA-418597 Reactome: R-HSA-432040 Reactome: R-HSA-5610787 Reactome: R-HSA-9634597 Reactome: R-HSA-9660821 Reactome: R-HSA-9664323
Cellular Localisation	Cell Membrane Multi-Pass Membrane Protein Cytoplasm Cell Projection Cilium Golgi Apparatus Also Detected In The Cytoplasm Close To Lipid Droplets
Alternative Antibody Names	Anti-Adenylate Cyclase Type 3 antibody Anti-Atp Pyrophosphate-Lyase 3 antibody Anti-Adenylate Cyclase Type Iii antibody Anti-Ac-Iii antibody Anti-Adenylate Cyclase - Olfactive Type antibody Anti-Adenylyl Cyclase 3 antibody Anti-Ac3 antibody Anti-ADCY3 antibody Anti-KIAA0511 antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance

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Anti-ADCY3 antibody (1-80) (STJ110180)