Anti-ADCY7 antibody (191-240 aa) (STJ91399) STJ91399 上海玉博生物科技有限公司

Anti-ADCY7 antibody (191-240 aa) (STJ91399)

如果您对该产品感兴趣的话，可以
产品名称：Anti-ADCY7 antibody (191-240 aa) (STJ91399)
产品型号：STJ91399
产品展商：ST john's laboratory
产品文档：无相关文档

简单介绍

Anti-ADCY7 antibody (191-240 aa) (STJ91399)

产品描述

Host:	Rabbit
Applications:	IHC/IF/ELISA
Reactivity:	Human/Mouse
Note:	STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description:	Rabbit polyclonal antibody anti-Adenylate cyclase type 7 (191-240 aa) is suitable for use in Immunohistochemistry, Immunofluorescence and ELISA research applications.

Clonality:	Polyclonal
Conjugation:	Unconjugated
Isotype:	IgG
Formulation:	Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide.
Purification:	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration:	1 mg/mL
Dilution Range:	IHC 1:100-1:300 IF 1:200-1:1000 ELISA 1:5000
Storage Instruction:	Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.

Gene Symbol:	ADCY7
Gene ID:	113
Uniprot ID:	ADCY7_HUMAN
Immunogen Region:	191-240 aa
Specificity:	A Cyclase VII Polyclonal Antibody detects endogenous levels of A Cyclase VII protein.
Immunogen:	The antiserum was produced against synthesized peptide derived from the human ADCY7 at the amino acid range 191-240

Function	Catalyzes the formation of cAMP in response to activation of G protein-coupled receptors (Probable). Functions in signaling cascades activated namely by thrombin and sphingosine 1-phosphate and mediates regulation of cAMP synthesis through synergistic action of the stimulatory G alpha protein with GNA13. Also, during inflammation, mediates zymosan-induced increase intracellular cAMP, leading to protein kinase A pathway activation in order to modulate innate immune responses through heterotrimeric G proteins G(12/13). Functions in signaling cascades activated namely by dopamine and C5 alpha chain and mediates regulation of cAMP synthesis through synergistic action of the stimulatory G protein with G beta:gamma complex. Functions, through cAMP response regulation, to keep inflammation under control during bacterial infection by sensing the presence of serum factors, such as the bioactive lysophospholipid (LPA) that regulate LPS-induced TNF-alpha production. However, it is also required for the optimal functions of B and T cells during adaptive immune responses by regulating cAMP synthesis in both B and T cells.
Protein Name	Adenylate Cyclase Type 7 Atp Pyrophosphate-Lyase 7 Adenylate Cyclase Type Vii Adenylyl Cyclase 7
Database Links	Reactome: R-HSA-163359 Reactome: R-HSA-163615 Reactome: R-HSA-164378 Reactome: R-HSA-170660 Reactome: R-HSA-170670 Reactome: R-HSA-418555 Reactome: R-HSA-418594 Reactome: R-HSA-418597 Reactome: R-HSA-432040 Reactome: R-HSA-5610787 Reactome: R-HSA-9634597 Reactome: R-HSA-9660821 Reactome: R-HSA-9664323
Cellular Localisation	Membrane Multi-Pass Membrane Protein
Alternative Antibody Names	Anti-Adenylate Cyclase Type 7 antibody Anti-Atp Pyrophosphate-Lyase 7 antibody Anti-Adenylate Cyclase Type Vii antibody Anti-Adenylyl Cyclase 7 antibody Anti-ADCY7 antibody Anti-KIAA0037 antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance

产品留言

标题

联系人

联系电话

内容

验证码

点击换一张

注：1.可以使用快捷键Alt+S或Ctrl+Enter发送信息!
2.如有必要,请您留下您的详细联系方式!

温馨提示：为规避购买风险，建议您在购买前务必确认供应商资质与产品质量。
免责申明：以上内容为注册会员自行发布，若信息的真实性、合法性存在争议，平台将会监督协助处理，欢迎举报

产品目录

产品资料

Anti-ADCY7 antibody (191-240 aa) (STJ91399)