Anti-ADM antibody (101-150 aa) (STJ96567) STJ96567 上海玉博生物科技有限公司

Anti-ADM antibody (101-150 aa) (STJ96567)

简单介绍

Anti-ADM antibody (101-150 aa) (STJ96567)

产品描述

Host:	Rabbit
Applications:	WB/IHC/IF/ELISA
Reactivity:	Human/Rat
Note:	STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description:	Rabbit polyclonal antibody anti-Pro-adrenomedullin (101-150 aa) is suitable for use in Western Blot, Immunohistochemistry, Immunofluorescence and ELISA research applications.

Clonality:	Polyclonal
Conjugation:	Unconjugated
Isotype:	IgG
Formulation:	Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide.
Purification:	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration:	1 mg/mL
Dilution Range:	WB 1:500-1:2000 IHC-P 1:100-300 ELISA 1:20000 IF 1:50-200
Storage Instruction:	Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.

Gene Symbol:	ADM
Gene ID:	133
Uniprot ID:	ADML_HUMAN
Immunogen Region:	101-150 aa
Specificity:	ADM Polyclonal Antibody detects endogenous levels of ADM protein.
Immunogen:	The antiserum was produced against synthesized peptide derived from the Internal region of human ADM at the amino acid range 101-150

Function	AM and PAMP are potent hypotensive and vasodilatator agents. Numerous actions have been reported most related to the physiologic control of fluid and electrolyte homeostasis. In the kidney, am is diuretic and natriuretic, and both am and pamp inhibit aldosterone secretion by direct adrenal actions. In pituitary gland, both peptides at physiologically relevant doses inhibit basal ACTH secretion. Both peptides appear to act in brain and pituitary gland to facilitate the loss of plasma volume, actions which complement their hypotensive effects in blood vessels.
Protein Name	Pro-Adrenomedullin Cleaved Into - Adrenomedullin Am - Proadrenomedullin N-20 Terminal Peptide Proam N-Terminal 20 Peptide Pamp Proam-N20
Database Links	Reactome: R-HSA-418555 Reactome: R-HSA-419812
Cellular Localisation	Secreted
Alternative Antibody Names	Anti-Pro-Adrenomedullin Cleaved Into - Adrenomedullin antibody Anti-Am - Proadrenomedullin N-20 Terminal Peptide antibody Anti-Proam N-Terminal 20 Peptide antibody Anti-Pamp antibody Anti-Proam-N20 antibody Anti-ADM antibody Anti-AM antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance

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