Human AGTR1 (Angiotensin II Receptor 1) Sandwich ELISA Kit (STJE0007005) STJE0007005 上海玉博生物科技有限公司

Human AGTR1 (Angiotensin II Receptor 1) Sandwich ELISA Kit (STJE0007005)

简单介绍

Human AGTR1 (Angiotensin II Receptor 1) Sandwich ELISA Kit (STJE0007005)

产品描述

Applications:	ELISA
Reactivity:	Human
Note:	STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Sensitivity:	0.055ng/mL
Detection Limit:	0.156-10ng/mL
Short Description:	This AGTR1 Sandwich ELISA Kit is an in-vitro enzyme-linked immunosorbent assay for the measurement of samples in human cell culture supernatant, serum and plasma (EDTA, citrate, heparin).

Storage Instruction:	Store the unopened kit in the fridge at 2-8°C for up to 6 months. Once opened store individual kit contents according to components table provided with the kit.
Assay Time:	4.5 hrs

Gene Symbol:	AGTR1
Gene ID:	185
Uniprot ID:	AGTR1_HUMAN
Sample Type:	tissue homogenates, cell lysates or other biological fluids.

Tissue Specificity	Liver, lung, adrenal and adrenocortical adenomas.
Post Translational Modifications	C-terminal Ser or Thr residues may be phosphorylated.
Function	Receptor for angiotensin II, a vasoconstricting peptide, which acts as a key regulator of blood pressure and sodium retention by the kidney. The activated receptor in turn couples to G-alpha proteins G(q) (GNAQ, GNA11, GNA14 or GNA15) and thus activates phospholipase C and increases the cytosolic Ca(2+) concentrations, which in turn triggers cellular responses such as stimulation of protein kinase C. (Microbial infection) During SARS coronavirus-2/SARS-CoV-2 infection, it is able to recognize and internalize the complex formed by secreted ACE2 and SARS-CoV-2 spike protein through DNM2/dynamin 2-dependent endocytosis.
Protein Name	Type-1 Angiotensin Ii Receptor At1ar At1br Angiotensin Ii Type-1 Receptor At1 Receptor
Database Links	Reactome: R-HSA-375276 Reactome: R-HSA-416476 Reactome: R-HSA-8856825 Reactome: R-HSA-8856828
Cellular Localisation	Cell Membrane Multi-Pass Membrane Protein
Alternative ELISA Names	Type-1 Angiotensin Ii Receptor ELISA kit At1ar ELISA kit At1br ELISA kit Angiotensin Ii Type-1 Receptor ELISA kit At1 Receptor ELISA kit AGTR1 ELISA kit AGTR1A ELISA kit AGTR1B ELISA kit AT2R1 ELISA kit AT2R1B ELISA kit
output

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance

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