KDM4C/GASC1/JMJD2C Positive Control peptide (STJ504331) STJ504331-5 上海玉博生物科技有限公司

KDM4C/GASC1/JMJD2C Positive Control peptide (STJ504331)

简单介绍

KDM4C/GASC1/JMJD2C Positive Control peptide (STJ504331)

产品描述

Applications:	WB
Note:	STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description:	KDM4C/GASC1/JMJD2C Positive Control is synthetically produced from the sequence and is suitable for use in western blot applications.

Formulation:	Provided as 100 uL ready-to-use, in SDS-PAGE sample buffer (Laemelli's buffer) containing Tris, pH 6.8, 1 % SDS, Glycerol and Bromophenolblue blue as tracking dye. The sample is reduced by adding 2% beta mercaptoethanol. The protein concentration is
Dilution Range:	WB: 1:2, 500-1:5, 000
Storage Instruction:	Store at-20°C for long term storage. Avoid freeze-thaw cycles.

Tissue Specificity	Overexpressed in several esophageal squamous cell carcinomas (ESCs).
Function	Histone demethylase that specifically demethylates 'Lys-9' and 'Lys-36' residues of histone H3, thereby playing a central role in histone code. Does not demethylate histone H3 'Lys-4', H3 'Lys-27' nor H4 'Lys-20'. Demethylates trimethylated H3 'Lys-9' and H3 'Lys-36' residue, while it has no activity on mono- and dimethylated residues. Demethylation of Lys residue generates formaldehyde and succinate.
Peptide Name	Lysine-Specific Demethylase 4c Gene Amplified In Squamous Cell Carcinoma 1 Protein Gasc-1 Protein Jmjc Domain-Containing Histone Demethylation Protein 3c Jumonji Domain-Containing Protein 2c Histone H3-Trimethyl-L-Lysine(9 Demethylase 4c
Database Links	Reactome: R-HSA-3214842 Reactome: R-HSA-5625886
Cellular Localisation	Nucleus
Alternative Peptide Names	Lysine-Specific Demethylase 4c protein Gene Amplified In Squamous Cell Carcinoma 1 Protein protein Gasc-1 Protein protein Jmjc Domain-Containing Histone Demethylation Protein 3c protein Jumonji Domain-Containing Protein 2c protein Histone H3-Trimethyl-L-Lysine(9 Demethylase 4c protein KDM4C protein GASC1 protein JHDM3C protein JMJD2C protein KIAA0780 protein

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance

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