PDE1C Blocking Peptide for STJ502241 peptide (STJ504609) STJ504609-250 上海玉博生物科技有限公司

PDE1C Blocking Peptide for STJ502241 peptide (STJ504609)

简单介绍

PDE1C Blocking Peptide for STJ502241 peptide (STJ504609)

产品描述

Applications:	Immunodepletion/Immunocompetition
Note:	STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description:	PDE1C Blocking Peptide for STJ502241 is synthetically produced from the sequence and is suitable for use in western blot applications.

Formulation:	Liquid form at 2.5mg/ml concentration in PBS. Up to 5% DMSO can be added. Orders with >1mg can be supplied in lyophilized powder form, or in buffer of choice.
Storage Instruction:	Store at-20°C for long term storage. Avoid freeze-thaw cycles.

Gene Symbol:	PDE1C
Gene ID:	5137
Uniprot ID:	PDE1C_HUMAN
Specificity:	This blocking peptide is recommended for use in combination with PDE1C antibody, STJ502241
Immunogen:	Synthetic peptide corresponding to unique amino acid sequence on PDE1C gene.

Tissue Specificity	Isoform PDE1C2 is present in the heart and brain and, at lower levels in the lung, liver, kidney and skeletal muscle. Isoform PDE1C1 is expressed in the heart and brain and, at lower levels in lung. Also expressed at low levels in uterus and testis.
Function	Calmodulin-dependent cyclic nucleotide phosphodiesterase with a dual specificity for the second messengers cAMP and cGMP, which are key regulators of many important physiological processes. Has a high affinity for both cAMP and cGMP. Modulates the amplitude and duration of the cAMP signal in sensory cilia in response to odorant stimulation, hence contributing to the generation of action potentials. Regulates smooth muscle cell proliferation. Regulates the stability of growth factor receptors, including PDGFRB (Probable).
Peptide Name	Dual Specificity Calcium/Calmodulin-Dependent 3' -5'-Cyclic Nucleotide Phosphodiesterase 1c Cam-Pde 1c Hcam3
Database Links	Reactome: R-HSA-111957
Cellular Localisation	Lysosome
Alternative Peptide Names	Dual Specificity Calcium/Calmodulin-Dependent 3' -5'-Cyclic Nucleotide Phosphodiesterase 1c protein Cam-Pde 1c protein Hcam3 protein PDE1C protein

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance

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