Anti-BDH2 antibody (STJA0004728) STJA0004728 上海玉博生物科技有限公司

Anti-BDH2 antibody (STJA0004728)

简单介绍

Anti-BDH2 antibody (STJA0004728)

产品描述

Host:	Rabbit
Applications:	WB/IHC/ELISA
Reactivity:	Human/Mouse/Rat
Note:	FOR SCIENTIFIC EDUCATIONAL RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR OTHER MEDICAL APPLICATIONS.
Short Description:	Rabbit polyclonal antibody anti-Dehydrogenase/Reductase Sdr Family Member 6 is suitable for use in Western Blot, Immunohistochemistry and ELISA research applications.

Clonality:	Polyclonal
Conjugation:	Unconjugated
Isotype:	IgG
Formulation:	PBS with 0.05% NaN3 and 40% Glycerol, pH7.4
Purification:	Antigen affinity purification
Concentration:	0.6 mg/mL
Dilution Range:	WB 1:500-1:2000, IHC 1:50-1:300
Storage Instruction:	Store at-20°C for long term, and avoid freeze-thaw cycles.

Tissue Specificity	Detected in liver (at protein level).
Function	NAD(H)-dependent dehydrogenase/reductase with a preference for cyclic substrates. Catalyzes stereoselective conversion of 4-oxo-L-proline to cis-4-hydroxy-L-proline, likely a detoxification mechanism for ketoprolines. Mediates the formation of 2,5-dihydroxybenzoate (2,5-DHBA), a siderophore that chelates free cytoplasmic iron and associates with LCN2, thereby regulating iron transport and homeostasis while protecting cells against free radical-induced oxidative stress. The iron-siderophore complex is imported into mitochondria, providing an iron source for mitochondrial metabolic processes in particular heme synthesis. May act as a 3-hydroxybutyrate dehydrogenase.
Protein Name	Dehydrogenase/Reductase Sdr Family Member 6 (R-Beta-Hydroxybutyrate Dehydrogenase 3-Hydroxybutyrate Dehydrogenase Type 2 4-Oxo-L-Proline Reductase Oxidoreductase Ucpa Short Chain Dehydrogenase/Reductase Family 15c Member 1
Database Links	Reactome: R-HSA-77111
Cellular Localisation	Cytoplasm
Alternative Antibody Names	Anti-Dehydrogenase/Reductase Sdr Family Member 6 antibody Anti-(R-Beta-Hydroxybutyrate Dehydrogenase antibody Anti-3-Hydroxybutyrate Dehydrogenase Type 2 antibody Anti-4-Oxo-L-Proline Reductase antibody Anti-Oxidoreductase Ucpa antibody Anti-Short Chain Dehydrogenase/Reductase Family 15c Member 1 antibody Anti-BDH2 antibody Anti-DHRS6 antibody Anti-SDR15C1 antibody Anti-UNQ6308 antibody Anti-PRO20933 antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance

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