Anti-AQP7 antibody (150-200) {FITC} (STJ500143) STJ500143-100 上海玉博生物科技有限公司

Anti-AQP7 antibody (150-200) {FITC} (STJ500143)

简单介绍

Anti-AQP7 antibody (150-200) {FITC} (STJ500143)

产品描述

Host:	Rabbit
Applications:	ELISA/IP/WB
Reactivity:	Bovine/Human/Mouse/Rat/Sheep
Note:	STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description:	Rabbit polyclonal antibody anti-AQP7 (150-200) is suitable for use in ELISA, Immunoprecipitation and Western Blot research applications.

Clonality:	Polyclonal
Conjugation:	FITC
Isotype:	IgG
Purification:	Affinity Purified
Concentration:	0.55-0.58 µg/µl
Dilution Range:	WB: 1:500 ELISA: 1:10, 000 IP: 1:200
Storage Instruction:	Store at-20°C for long term storage. Avoid freeze-thaw cycles.

Gene Symbol:	Aqp7
Gene ID:	11832
Uniprot ID:	AQP7_MOUSE
Immunogen Region:	150-200
Immunogen:	Synthetic amidated peptide taken within amino acid region 150-200 on rat Aquaporin 7 protein, covalently modified and conjugated to KLH.

Tissue Specificity	Detected in proximal tubules in kidney. Detected in the capillary network between muscle fibers in skeletal muscle and heart, and in spermatids and on spermatozoa tails in testis and epididymis. Detected in white and brown adipose tissue, especially on small blood vessels (at protein level). Detected in kidney and white adipose tissue.
Function	Forms a channel that mediates water and glycerol transport across cell membranes at neutral pH. The channel is also permeable to urea. Plays an important role in body energy homeostasis under conditions that promote lipid catabolism, giving rise to glycerol and free fatty acids. Mediates glycerol export from adipocytes. After release into the blood stream, glycerol is used for gluconeogenesis in the liver to maintain normal blood glucose levels and prevent fasting hypoglycemia. Required for normal glycerol reabsorption in the kidney.
Protein Name	Aquaporin-7 Aqp-7 Aquaglyceroporin-7
Database Links	Reactome: R-MMU-432030 Reactome: -MMU-432047
Cellular Localisation	Cell Membrane Multi-Pass Membrane Protein Cytoplasm Cell Cortex Cytoplasmic Vesicle Membrane Lipid Droplet Internalized From The Cell Membrane In Response To Catecholamine-Induced Activation Of Pka Detected On Intracellular Membranes And Colocalizes With Lipid Droplets Colocalizes With Plin1 In Adipocytes Probably On Lipid Droplets
Alternative Antibody Names	Anti-Aquaporin-7 antibody Anti-Aqp-7 antibody Anti-Aquaglyceroporin-7 antibody Anti-Aqp7 antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance

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