Human FBLIM1 (Filamin Binding LIM Protein 1) Sandwich ELISA Kit (STJE0008807) STJE0008807 上海玉博生物科技有限公司

Human FBLIM1 (Filamin Binding LIM Protein 1) Sandwich ELISA Kit (STJE0008807)

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产品名称：Human FBLIM1 (Filamin Binding LIM Protein 1) Sandwich ELISA Kit (STJE0008807)
产品型号：STJE0008807
产品展商：ST john's laboratory
产品文档：无相关文档

简单介绍

Human FBLIM1 (Filamin Binding LIM Protein 1) Sandwich ELISA Kit (STJE0008807)

产品描述

Applications:	ELISA
Reactivity:	Human
Note:	STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Sensitivity:	0.062ng/mL
Detection Limit:	0.156-10ng/mL
Short Description:	This FBLIM1 Sandwich ELISA Kit is an in-vitro enzyme-linked immunosorbent assay for the measurement of samples in human cell culture supernatant, serum and plasma (EDTA, citrate, heparin).

Storage Instruction:	Store the unopened kit in the fridge at 2-8°C for up to 6 months. Once opened store individual kit contents according to components table provided with the kit.
Assay Time:	4.5 hrs

Gene Symbol:	FBLIM1
Gene ID:	54751
Uniprot ID:	FBLI1_HUMAN
Sample Type:	serum, plasma, tissue homogenates or other biological fluids.

Tissue Specificity	Isoform 1 and isoform 3 are expressed in heart, kidney, lung, pancreas, placenta and platelets. Isoform 2 is expressed in brain, heart, kidney, lung, pancreas, placenta, skeletal muscle and platelets.
Post Translational Modifications
Function	Serves as an anchoring site for cell-ECM adhesion proteins and filamin-containing actin filaments. Is implicated in cell shape modulation (spreading) and motility. May participate in the regulation of filamin-mediated cross-linking and stabilization of actin filaments. May also regulate the assembly of filamin-containing signaling complexes that control actin assembly. Promotes dissociation of FLNA from ITGB3 and ITGB7. Promotes activation of integrins and regulates integrin-mediated cell-cell adhesion.
Protein Name	Filamin-Binding Lim Protein 1 Fblp-1 Migfilin Mitogen-Inducible 2-Interacting Protein Mig2-Interacting Protein
Database Links	Reactome: R-HSA-446353
Cellular Localisation	Cell Junction Focal Adhesion Cytoplasm Cytoskeleton Stress Fiber Associated With Actin Stress Fiber At Cell-Ecm Focal Adhesion Sites Isoform 1 And Isoform 3 Are Recruited And Localized At Actin Stress Fibers And Clustered At Cell-Emc Adhesion Sites Through Interaction With Fermt2 Isoform 2 Is Localized At Actin Stress Fibers
Alternative ELISA Names	Filamin-Binding Lim Protein 1 ELISA kit Fblp-1 ELISA kit Migfilin ELISA kit Mitogen-Inducible 2-Interacting Protein ELISA kit Mig2-Interacting Protein ELISA kit FBLIM1 ELISA kit FBLP1 ELISA kit
output

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance

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