Human FFAR1 (Free Fatty Acid Receptor 1) Sandwich ELISA Kit (STJE0008844) STJE0008844 上海玉博生物科技有限公司

Human FFAR1 (Free Fatty Acid Receptor 1) Sandwich ELISA Kit (STJE0008844)

简单介绍

Human FFAR1 (Free Fatty Acid Receptor 1) Sandwich ELISA Kit (STJE0008844)

产品描述

Applications:	ELISA
Reactivity:	Human
Note:	STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Sensitivity:	0.54ng/mL
Detection Limit:	1.56-100ng/mL
Short Description:	This FFAR1 Sandwich ELISA Kit is an in-vitro enzyme-linked immunosorbent assay for the measurement of samples in human cell culture supernatant, serum and plasma (EDTA, citrate, heparin).

Storage Instruction:	Store the unopened kit in the fridge at 2-8°C for up to 6 months. Once opened store individual kit contents according to components table provided with the kit.
Assay Time:	4.5 hrs

Gene Symbol:	FFAR1
Gene ID:	2864
Uniprot ID:	FFAR1_HUMAN
Sample Type:	serum, plasma, tissue homogenates or other biological fluids.

Tissue Specificity	Detected in brain and pancreas. Detected in pancreatic beta cells.
Post Translational Modifications
Function	G-protein coupled receptor for medium and long chain saturated and unsaturated fatty acids that plays an important role in glucose homeostasis. Fatty acid binding increases glucose-stimulated insulin secretion, and may also enhance the secretion of glucagon-like peptide 1 (GLP-1). May also play a role in bone homeostasis.receptor signaling activates pathways that inhibit osteoclast differentiation. Ligand binding leads to a conformation change that triggers signaling via G-proteins that activate phospholipase C, leading to an increase of the intracellular calcium concentration. Seems to act through a G(q) and G(i)-mediated pathway. Mediates the anti-inflammatory effects of omega-3 polyunsaturated fatty acids (PUFAs) via inhibition of NLRP3 inflammasome activation.
Protein Name	Free Fatty Acid Receptor 1 G-Protein Coupled Receptor 40
Database Links	Reactome: R-HSA-381771 Reactome: R-HSA-400511 Reactome: R-HSA-416476 Reactome: R-HSA-434316 Reactome: R-HSA-444209
Cellular Localisation	Cell Membrane Multi-Pass Membrane Protein
Alternative ELISA Names	Free Fatty Acid Receptor 1 ELISA kit G-Protein Coupled Receptor 40 ELISA kit FFAR1 ELISA kit GPR40 ELISA kit
output

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance

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