Anti-BIN2 antibody (260-340 aa) (STJ191822) STJ191822 上海玉博生物科技有限公司

Anti-BIN2 antibody (260-340 aa) (STJ191822)

简单介绍

Anti-BIN2 antibody (260-340 aa) (STJ191822)

产品描述

Host:	Rabbit
Applications:	WB/ELISA
Reactivity:	Human/Rat/Mouse
Note:	STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description:	Rabbit polyclonal antibody anti-Bridging integrator 2 (260-340 aa) is suitable for use in Western Blot and ELISA research applications.

Clonality:	Polyclonal
Conjugation:	Unconjugated
Isotype:	IgG
Formulation:	Liquid in PBS containing 50% Glycerol and 0.02% Sodium Azide.
Purification:	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration:	1 mg/mL
Dilution Range:	WB 1:500-2000 ELISA 1:5000-20000
Storage Instruction:	Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.

Gene Symbol:	BIN2
Gene ID:	51411
Uniprot ID:	BIN2_HUMAN
Immunogen Region:	260-340 aa
Specificity:	BIN2 Polyclonal Antibody detects endogenous levels of protein.
Immunogen:	Synthesized peptide derived from the human protein at the amino acid range 260-340

Function	Promotes cell motility and migration, probably via its interaction with the cell membrane and with podosome proteins that mediate interaction with the cytoskeleton. Modulates membrane curvature and mediates membrane tubulation. Plays a role in podosome formation. Inhibits phagocytosis.
Protein Name	Bridging Integrator 2 Breast Cancer-Associated Protein 1
Database Links	Reactome: R-HSA-6798695 Reactome: R-HSA-9673768
Cellular Localisation	Cytoplasm Cell Projection Podosome Membrane Peripheral Membrane Protein Cytoplasmic Side Cell Cortex Phagocytic Cup Associates With Membranes Enriched In Phosphoinositides Detected In The Actin-Rich Cell Cortex At The Leading Edge Of Migrating Cells Detected At Podosomes At An Actin-Rich Ring-Like Structure
Alternative Antibody Names	Anti-Bridging Integrator 2 antibody Anti-Breast Cancer-Associated Protein 1 antibody Anti-BIN2 antibody Anti-BRAP1 antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance

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