Human FKBP5 (FK506 Binding Protein 5) Sandwich ELISA Kit (STJE0008934) STJE0008934 上海玉博生物科技有限公司

Human FKBP5 (FK506 Binding Protein 5) Sandwich ELISA Kit (STJE0008934)

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产品名称：Human FKBP5 (FK506 Binding Protein 5) Sandwich ELISA Kit (STJE0008934)
产品型号：STJE0008934
产品展商：ST john's laboratory
产品文档：无相关文档

简单介绍

Human FKBP5 (FK506 Binding Protein 5) Sandwich ELISA Kit (STJE0008934)

产品描述

Applications:	ELISA
Reactivity:	Human
Note:	STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Sensitivity:	0.061ng/mL
Detection Limit:	0.156-10ng/mL
Short Description:	This FKBP5 Sandwich ELISA Kit is an in-vitro enzyme-linked immunosorbent assay for the measurement of samples in human cell culture supernatant, serum and plasma (EDTA, citrate, heparin).

Storage Instruction:	Store the unopened kit in the fridge at 2-8°C for up to 6 months. Once opened store individual kit contents according to components table provided with the kit.
Assay Time:	4.5 hrs

Gene Symbol:	FKBP5
Gene ID:	2289
Uniprot ID:	FKBP5_HUMAN
Sample Type:	serum, plasma, tissue homogenates or other biological fluids.

Tissue Specificity	Widely expressed, enriched in testis compared to other tissues.
Post Translational Modifications	Acetylation impairs ability to promote interaction between Akt/AKT1 and PHLPP1. Deacetylation by SIRT7 promotes interaction between Akt/AKT1 and PHLPP1, leading to suppress Akt/AKT1 activation.
Function	Immunophilin protein with PPIase and co-chaperone activities. Component of unligated steroid receptors heterocomplexes through interaction with heat-shock protein 90 (HSP90). Plays a role in the intracellular trafficking of heterooligomeric forms of steroid hormone receptors maintaining the complex into the cytoplasm when unliganded. Acts as a regulator of Akt/AKT1 activity by promoting the interaction between Akt/AKT1 and PHLPP1, thereby enhancing dephosphorylation and subsequent activation of Akt/AKT1. Interacts with IKBKE and IKBKB which facilitates IKK complex assembly leading to increased IKBKE and IKBKB kinase activity, NF-kappaB activation, and IFN production.
Protein Name	Peptidyl-Prolyl Cis-Trans Isomerase Fkbp5 Ppiase Fkbp5 51 Kda Fk506-Binding Protein 51 Kda Fkbp Fkbp-51 54 Kda Progesterone Receptor-Associated Immunophilin Androgen-Regulated Protein 6 Ff1 Antigen Fk506-Binding Protein 5 Fkbp-5 Fkbp54 P54 Hsp90-Binding Immunophilin Rotamase
Database Links	Reactome: R-HSA-3371497 Reactome: R-HSA-8939211 Reactome: R-HSA-9022699
Cellular Localisation	Cytoplasm Nucleus
Alternative ELISA Names	Peptidyl-Prolyl Cis-Trans Isomerase Fkbp5 ELISA kit Ppiase Fkbp5 ELISA kit 51 Kda Fk506-Binding Protein ELISA kit 51 Kda Fkbp ELISA kit Fkbp-51 ELISA kit 54 Kda Progesterone Receptor-Associated Immunophilin ELISA kit Androgen-Regulated Protein 6 ELISA kit Ff1 Antigen ELISA kit Fk506-Binding Protein 5 ELISA kit Fkbp-5 ELISA kit Fkbp54 ELISA kit P54 ELISA kit Hsp90-Binding Immunophilin ELISA kit Rotamase ELISA kit FKBP5 ELISA kit AIG6 ELISA kit FKBP51 ELISA kit
output

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance

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Human FKBP5 (FK506 Binding Protein 5) Sandwich ELISA Kit (STJE0008934)