Anti-BMPR1A antibody (1-50 aa) (STJ96893) STJ96893 上海玉博生物科技有限公司

Anti-BMPR1A antibody (1-50 aa) (STJ96893)

简单介绍

Anti-BMPR1A antibody (1-50 aa) (STJ96893)

产品描述

Host:	Rabbit
Applications:	WB/ELISA
Reactivity:	Human/Rat/Mouse
Note:	STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description:	Rabbit polyclonal antibody anti-Bone morphogenetic protein receptor type-1A (1-50 aa) is suitable for use in Western Blot and ELISA research applications.

Clonality:	Polyclonal
Conjugation:	Unconjugated
Isotype:	IgG
Formulation:	Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide.
Purification:	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration:	1 mg/mL
Dilution Range:	WB 1:500-1:2000 ELISA 1:20000
Storage Instruction:	Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.

Gene Symbol:	BMPR1A
Gene ID:	657
Uniprot ID:	BMR1A_HUMAN
Immunogen Region:	1-50 aa
Specificity:	CD292 Polyclonal Antibody detects endogenous levels of CD292 protein.
Immunogen:	The antiserum was produced against synthesized peptide derived from the N-terminal region of human BMPR1A at the amino acid range 1-50

Post Translational Modifications	Glycosylated.
Function	On ligand binding, forms a receptor complex consisting of two type II and two type I transmembrane serine/threonine kinases. Type II receptors phosphorylate and activate type I receptors which autophosphorylate, then bind and activate SMAD transcriptional regulators. Receptor for BMP2, BMP4, GDF5 and GDF6. Positively regulates chondrocyte differentiation through GDF5 interaction. Mediates induction of adipogenesis by GDF6. May promote the expression of HAMP, potentially via its interaction with BMP2.
Protein Name	Bone Morphogenetic Protein Receptor Type-1a Bmp Type-1a Receptor Bmpr-1a Activin Receptor-Like Kinase 3 Alk-3 Serine/Threonine-Protein Kinase Receptor R5 Skr5 Cd Antigen Cd292
Database Links	Reactome: R-HSA-201451
Cellular Localisation	Cell Membrane Single-Pass Type I Membrane Protein Cell Surface
Alternative Antibody Names	Anti-Bone Morphogenetic Protein Receptor Type-1a antibody Anti-Bmp Type-1a Receptor antibody Anti-Bmpr-1a antibody Anti-Activin Receptor-Like Kinase 3 antibody Anti-Alk-3 antibody Anti-Serine/Threonine-Protein Kinase Receptor R5 antibody Anti-Skr5 antibody Anti-Cd Antigen Cd292 antibody Anti-BMPR1A antibody Anti-ACVRLK3 antibody Anti-ALK3 antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance

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