Anti-BMPR1B antibody (21-70 aa) (STJ98998) STJ98998 上海玉博生物科技有限公司

Anti-BMPR1B antibody (21-70 aa) (STJ98998)

简单介绍

Anti-BMPR1B antibody (21-70 aa) (STJ98998)

产品描述

Host:	Rabbit
Applications:	IHC/IF/ELISA
Reactivity:	Human/Mouse
Note:	STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description:	Rabbit polyclonal antibody anti-Bone morphogenetic protein receptor type-1B (21-70 aa) is suitable for use in Immunohistochemistry, Immunofluorescence and ELISA research applications.

Clonality:	Polyclonal
Conjugation:	Unconjugated
Isotype:	IgG
Formulation:	Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide.
Purification:	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration:	1 mg/mL
Dilution Range:	IHC-P 1:50-200 ELISA 1:10000-20000 IF 1:50-200
Storage Instruction:	Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.

Gene Symbol:	BMPR1B
Gene ID:	658
Uniprot ID:	BMR1B_HUMAN
Immunogen Region:	21-70 aa
Specificity:	The antibody detects endogenous BMPR-IB
Immunogen:	Synthetic peptide from the human protein at the amino acid range 21-70

Function	On ligand binding, forms a receptor complex consisting of two type II and two type I transmembrane serine/threonine kinases. Type II receptors phosphorylate and activate type I receptors which autophosphorylate, then bind and activate SMAD transcriptional regulators. Receptor for BMP7/OP-1 and GDF5. Positively regulates chondrocyte differentiation through GDF5 interaction.
Protein Name	Bone Morphogenetic Protein Receptor Type-1b Bmp Type-1b Receptor Bmpr-1b Cd Antigen Cdw293
Database Links	Reactome: R-HSA-201451
Cellular Localisation	Cell Membrane Single-Pass Type I Membrane Protein
Alternative Antibody Names	Anti-Bone Morphogenetic Protein Receptor Type-1b antibody Anti-Bmp Type-1b Receptor antibody Anti-Bmpr-1b antibody Anti-Cd Antigen Cdw293 antibody Anti-BMPR1B antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance

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