Anti-BNIP1 antibody (1-200) (STJ29404) STJ29404 上海玉博生物科技有限公司

Anti-BNIP1 antibody (1-200) (STJ29404)

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产品名称：Anti-BNIP1 antibody (1-200) (STJ29404)
产品型号：STJ29404
产品展商：ST john's laboratory
产品文档：无相关文档

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Anti-BNIP1 antibody (1-200) (STJ29404)

产品描述

Host:	Rabbit
Applications:	WB
Reactivity:	Human/Mouse/Rat
Note:	STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description:	Rabbit polyclonal antibody anti-BNIP1 (1-200) is suitable for use in Western Blot research applications.

Clonality:	Polyclonal
Conjugation:	Unconjugated
Isotype:	IgG
Formulation:	PBS with 0.02% Sodium Azide, 50% Glycerol, pH7.3.
Purification:	Affinity purification
Dilution Range:	WB 1:500-1:2000
Storage Instruction:	Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.

Gene Symbol:	BNIP1
Gene ID:	662
Uniprot ID:	SEC20_HUMAN
Immunogen Region:	1-200
Immunogen:	Recombinant fusion protein containing a sequence corresponding to amino acids 1-200 of human BNIP1 (NP_001196.2).
Immunogen Sequence:	MAAPQDVHVRICNQEIVKFD LEVKALIQDIRDCSGPLSAL TELNTKVKEKFQQLRHRIQD LEQLAKEQDKESEKQLLLQE VENHKKQMLSNQASWRKANL TCKIAIDNLEKAELLQGGDL LRQRKTTKESLAQTSSTITE SLMGISRMMAQQVQQSEEAM QSLVTSSRTILDANEEFKSM SGTIQLGRKLITKYNRRELT

Tissue Specificity	Isoform 1 is highly expressed in heart, brain, liver skeletal muscle and pancreas. Isoform 3 is moderately expressed in placenta, lung and kidney. Isoform 4 is highly expressed in testis and small intestine.
Post Translational Modifications	Polyubiquitinated. 'Lys-63'-linked polyubiquitination by RNF185 increases the interaction with the autophagy receptor SQSTM1. Undergoes 'Lys-29'- and 'Lys-63'-linked polyubiquitination by RNF186 that may regulate BNIP1 localization to the mitochondrion.
Function	As part of a SNARE complex may be involved in endoplasmic reticulum membranes fusion and be required for the maintenance of endoplasmic reticulum organization. Also plays a role in apoptosis. It is for instance required for endoplasmic reticulum stress-induced apoptosis. As a substrate of RNF185 interacting with SQSTM1, might also be involved in mitochondrial autophagy (Probable).
Protein Name	Vesicle Transport Protein Sec20 Bcl2/Adenovirus E1b 19 Kda Protein-Interacting Protein 1 Transformation-Related Gene 8 Protein Trg-8
Database Links	Reactome: R-HSA-6811434
Cellular Localisation	Endoplasmic Reticulum Membrane Single-Pass Type Iv Membrane Protein Mitochondrion Membrane Localization To The Mitochondrion Is Regulated By Rnf186
Alternative Antibody Names	Anti-Vesicle Transport Protein Sec20 antibody Anti-Bcl2/Adenovirus E1b 19 Kda Protein-Interacting Protein 1 antibody Anti-Transformation-Related Gene 8 Protein antibody Anti-Trg-8 antibody Anti-BNIP1 antibody Anti-NIP1 antibody Anti-SEC20L antibody Anti-TRG8 antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance

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Anti-BNIP1 antibody (1-200) (STJ29404)