Anti-BNIP3L antibody (STJ192181) STJ192181 上海玉博生物科技有限公司

Anti-BNIP3L antibody (STJ192181)

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产品名称：Anti-BNIP3L antibody (STJ192181)
产品型号：STJ192181
产品展商：ST john's laboratory
产品文档：无相关文档

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Anti-BNIP3L antibody (STJ192181)

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Host:	Rabbit
Applications:	WB/ELISA
Reactivity:	Human/Mouse
Note:	STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description:	Rabbit polyclonal antibody anti-BCL2/adenovirus E1B 19 kDa protein-interacting protein 3-like is suitable for use in Western Blot and ELISA research applications.

Clonality:	Polyclonal
Conjugation:	Unconjugated
Isotype:	IgG
Formulation:	Liquid in PBS containing 50% Glycerol and 0.02% Sodium Azide.
Purification:	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration:	1 mg/mL
Dilution Range:	WB 1:500-2000 ELISA 1:5000-20000
Storage Instruction:	Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.

Gene Symbol:	BNIP3L
Gene ID:	665
Uniprot ID:	BNI3L_HUMAN
Specificity:	BNI3L Polyclonal Antibody detects endogenous levels of protein.
Immunogen:	Synthesized peptide derived from part of the human protein

Function	Induces apoptosis. Interacts with viral and cellular anti-apoptosis proteins. Can overcome the suppressors BCL-2 and BCL-XL, although high levels of BCL-XL expression will inhibit apoptosis. Inhibits apoptosis induced by BNIP3. Involved in mitochondrial quality control via its interaction with SPATA18/MIEAP: in response to mitochondrial damage, participates in mitochondrial protein catabolic process (also named MALM) leading to the degradation of damaged proteins inside mitochondria. The physical interaction of SPATA18/MIEAP, BNIP3 and BNIP3L/NIX at the mitochondrial outer membrane regulates the opening of a pore in the mitochondrial double membrane in order to mediate the translocation of lysosomal proteins from the cytoplasm to the mitochondrial matrix. May function as a tumor suppressor.
Protein Name	Bcl2/Adenovirus E1b 19 Kda Protein-Interacting Protein 3-Like Adenovirus E1b19k-Binding Protein B5 Bcl2/Adenovirus E1b 19 Kda Protein-Interacting Protein 3a Nip3-Like Protein X Nip3l
Database Links	Reactome: R-HSA-6803204
Cellular Localisation	Nucleus Envelope Endoplasmic Reticulum Mitochondrion Outer Membrane Membrane Single-Pass Membrane Protein Colocalizes With Spata18 At The Mitochondrion Outer Membrane
Alternative Antibody Names	Anti-Bcl2/Adenovirus E1b 19 Kda Protein-Interacting Protein 3-Like antibody Anti-Adenovirus E1b19k-Binding Protein B5 antibody Anti-Bcl2/Adenovirus E1b 19 Kda Protein-Interacting Protein 3a antibody Anti-Nip3-Like Protein X antibody Anti-Nip3l antibody Anti-BNIP3L antibody Anti-BNIP3A antibody Anti-BNIP3H antibody Anti-NIX antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance

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Anti-BNIP3L antibody (STJ192181)