Anti-ARL2 antibody (C-Term) (STJ70220) STJ70220-100 上海玉博生物科技有限公司

Anti-ARL2 antibody (C-Term) (STJ70220)

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产品名称：Anti-ARL2 antibody (C-Term) (STJ70220)
产品型号：STJ70220-100
产品展商：ST john's laboratory
产品文档：无相关文档

简单介绍

Anti-ARL2 antibody (C-Term) (STJ70220)

产品描述

Host:	Goat
Applications:	Pep-ELISA/WB/IF/FC
Reactivity:	Human/Dog
Note:	STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description:	Goat polyclonal antibody anti-ARL2 (C-Term) is suitable for use in ELISA, Western Blot, Immunofluorescence and Flow Cytometry research applications.

Clonality:	Polyclonal
Conjugation:	Unconjugated
Isotype:	IgG
Formulation:	0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. NA
Purification:	Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Concentration:	0.5 mg/mL
Dilution Range:	WB-Recommended for use at 1-3µg/ml ELISA-antibody detection limit dilution 1:1000.
Storage Instruction:	Store at-20°C on receipt and minimise freeze-thaw cycles.

Gene Symbol:	ARL2
Gene ID:	402
Uniprot ID:	ARL2_HUMAN
Immunogen Region:	C-Term
Accession Number:	NP_001658.2
Immunogen Sequence:	LDDISSRIFTAD

Function	Small GTP-binding protein which cycles between an inactive GDP-bound and an active GTP-bound form, and the rate of cycling is regulated by guanine nucleotide exchange factors (GEF) and GTPase-activating proteins (GAP). GTP-binding protein that does not act as an allosteric activator of the cholera toxin catalytic subunit. Regulates formation of new microtubules and centrosome integrity. Prevents the TBCD-induced microtubule destruction. Participates in association with TBCD, in the disassembly of the apical junction complexes. Antagonizes the effect of TBCD on epithelial cell detachment and tight and adherens junctions disassembly. Together with ARL2, plays a role in the nuclear translocation, retention and transcriptional activity of STAT3. Component of a regulated secretory pathway involved in Ca(2+)-dependent release of acetylcholine. Required for normal progress through the cell cycle. Also regulates mitochondrial integrity and function.
Protein Name	Adp-Ribosylation Factor-Like Protein 2
Database Links	Reactome: R-HSA-389977 Reactome: R-HSA-83936 Reactome: R-HSA-9648002
Cellular Localisation	Mitochondrion Intermembrane Space Cytoplasm Cytoskeleton Microtubule Organizing Center Centrosome Nucleus The Complex Formed With Arl2bp Arl2 And Slc25a6 Is Expressed In Mitochondria Arl2 And Slc25a4 Is Expressed In Mitochondria Not Detected In The Golgi Nucleus And On The Mitotic Spindle Centrosome-Associated Throughout The Cell Cycle Not Detected To Interphase Microtubules
Alternative Antibody Names	Anti-Adp-Ribosylation Factor-Like Protein 2 antibody Anti-ARL2 antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance

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Anti-ARL2 antibody (C-Term) (STJ70220)