Anti-Arl6/BBS3-Mouse antibody (Internal) (STJ72456) STJ72456-100 上海玉博生物科技有限公司

Anti-Arl6/BBS3-Mouse antibody (Internal) (STJ72456)

简单介绍

Anti-Arl6/BBS3-Mouse antibody (Internal) (STJ72456)

产品描述

Host:	Goat
Applications:	Pep-ELISA/IHC
Reactivity:	Mouse/Rat/Cow/Dog
Note:	STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description:	Goat polyclonal antibody anti-Arl6/BBS3-Mouse (Internal) is suitable for use in ELISA and Immunohistochemistry research applications.

Clonality:	Polyclonal
Conjugation:	Unconjugated
Isotype:	IgG
Formulation:	0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. NA
Purification:	Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Concentration:	0.5 mg/mL
Dilution Range:	IHC-5µg/ml ELISA-antibody detection limit dilution 1:16000.
Storage Instruction:	Store at-20°C on receipt and minimise freeze-thaw cycles.

Immunogen Region:	Internal
Accession Number:	NP_062639.3
Specificity:	Reported variants represent identical protein: NP_816931.1, NP_115522.1
Immunogen Sequence:	KPSNAQSQDIVPT

Function	Involved in membrane protein trafficking at the base of the ciliary organelle. Mediates recruitment onto plasma membrane of the BBSome complex which would constitute a coat complex required for sorting of specific membrane proteins to the primary cilia. Together with BBS1, is necessary for correct trafficking of PKD1 to primary cilia. Together with the BBSome complex and LTZL1, controls SMO ciliary trafficking and contributes to the sonic hedgehog (SHH) pathway regulation. May regulate cilia assembly and disassembly and subsequent ciliary signaling events such as the Wnt signaling cascade. Isoform 2 may be required for proper retinal function and organization.
Protein Name	Adp-Ribosylation Factor-Like Protein 6
Database Links	Reactome: R-MMU-5620922
Cellular Localisation	Cell Projection Cilium Membrane Peripheral Membrane Protein Cytoplasmic Side Cytoplasm Cytoskeleton Cilium Axoneme Cilium Basal Body Appears In A Pattern Of Punctae Flanking The Microtubule Axoneme That Likely Correspond To Small Membrane-Associated Patches Localizes To The So-Called Ciliary Gate Where Vesicles Carrying Ciliary Cargo Fuse With The Membrane
Alternative Antibody Names	Anti-Adp-Ribosylation Factor-Like Protein 6 antibody Anti-Arl6 antibody Anti-Bbs3 antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance

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