Anti-ARL6IP1 antibody (STJA0008940) STJA0008940 上海玉博生物科技有限公司

Anti-ARL6IP1 antibody (STJA0008940)

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产品名称：Anti-ARL6IP1 antibody (STJA0008940)
产品型号：STJA0008940
产品展商：ST john's laboratory
产品文档：无相关文档

简单介绍

Anti-ARL6IP1 antibody (STJA0008940)

产品描述

Host:	Rabbit
Applications:	WB
Reactivity:	Human/Mouse
Note:	STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description:	Rabbit polyclonal antibody anti-ADP-ribosylation factor-like protein 6-interacting protein 1 is suitable for use in Western Blot research applications.

Clonality:	Polyclonal
Conjugation:	Unconjugated
Isotype:	IgG
Formulation:	Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide.
Purification:	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration:	1 mg/mL
Dilution Range:	WB 1:500-2000
Storage Instruction:	Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.

Gene Symbol:	ARL6IP1
Gene ID:	23204
Uniprot ID:	AR6P1_HUMAN
Specificity:	This antibody detects endogenous levels of ARMER at Human, Mouse
Immunogen:	Synthesized peptide derived from human ARMER

Function	Positively regulates SLC1A1/EAAC1-mediated glutamate transport by increasing its affinity for glutamate in a PKC activity-dependent manner. Promotes the catalytic efficiency of SLC1A1/EAAC1 probably by reducing its interaction with ARL6IP5, a negative regulator of SLC1A1/EAAC1-mediated glutamate transport. Plays a role in the formation and stabilization of endoplasmic reticulum tubules. Negatively regulates apoptosis, possibly by modulating the activity of caspase-9 (CASP9). Inhibits cleavage of CASP9-dependent substrates and downstream markers of apoptosis but not CASP9 itself. May be involved in protein transport, membrane trafficking, or cell signaling during hematopoietic maturation.
Protein Name	Adp-Ribosylation Factor-Like Protein 6-Interacting Protein 1 Arl-6-Interacting Protein 1 Aip-1 Apoptotic Regulator In The Membrane Of The Endoplasmic Reticulum
Cellular Localisation	Endomembrane System Multi-Pass Membrane Protein Endoplasmic Reticulum Membrane Endoplasmic Reticulum Predominantly Localized To Intracytoplasmic Membranes Preferentially Localizes At The Er Tubules And The Edge Of The Er Sheets Both Of Which Are Characterized By A High Membrane Curvature
Alternative Antibody Names	Anti-Adp-Ribosylation Factor-Like Protein 6-Interacting Protein 1 antibody Anti-Arl-6-Interacting Protein 1 antibody Anti-Aip-1 antibody Anti-Apoptotic Regulator In The Membrane Of The Endoplasmic Reticulum antibody Anti-ARL6IP1 antibody Anti-ARL6IP antibody Anti-ARMER antibody Anti-KIAA0069 antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance

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Anti-ARL6IP1 antibody (STJA0008940)