Human FUT4 (Fucosyltransferase 4) Sandwich ELISA Kit Ready-To-Use (STJE0015388) STJE0015388 上海玉博生物科技有限公司

Human FUT4 (Fucosyltransferase 4) Sandwich ELISA Kit Ready-To-Use (STJE0015388)

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产品名称：Human FUT4 (Fucosyltransferase 4) Sandwich ELISA Kit Ready-To-Use (STJE0015388)
产品型号：STJE0015388
产品展商：ST john's laboratory
产品文档：无相关文档

简单介绍

Human FUT4 (Fucosyltransferase 4) Sandwich ELISA Kit Ready-To-Use (STJE0015388)

产品描述

Applications:	ELISA
Reactivity:	Human
Note:	STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Sensitivity:	0.062ng/mL
Detection Limit:	0.156-10ng/mL
Short Description:	This FUT4 Sandwich ELISA Kit, Ready-To-Use is an in-vitro enzyme-linked immunosorbent assay for the measurement of samples in human cell culture supernatant, serum and plasma (EDTA, citrate, heparin).

Storage Instruction:	The whole kit may be stored at-20°C for up to 12 months from receipt. An unopened kit may be stored in the fridge at 2-8°C for up to 6 months. Once opened store individual kit contents according to components table provided with the kit.
Assay Time:	3 hrs

Gene Symbol:	FUT4
Gene ID:	2526
Uniprot ID:	FUT4_HUMAN
Immunogen Region:	Ready-To-Use
Sample Type:	tissue homogenates or other biological fluids.

Tissue Specificity	Isoform Short: Expressed at low levels in bone marrow-derived mesenchymal stem cells. Expressed in cord blood immature promyelocytes and in peripheral blood myeloid and lymphoid cell populations.
Post Translational Modifications
Function	Isoform Short: Catalyzes alpha(1->3) linkage of fucosyl moiety transferred from GDP-beta-L-fucose to N-acetyl glucosamine (GlcNAc) within type 2 lactosamine (LacNAc, Gal-beta(1->4)GlcNAc) glycan attached to N- or O-linked glycoproteins. Robustly fucosylates nonsialylated distal LacNAc unit of the polylactosamine chain to form Lewis X antigen (CD15), a glycan determinant known to mediate important cellular functions in development and immunity. Fucosylates with lower efficiency sialylated LacNAc acceptors to form sialyl Lewis X and 6-sulfo sialyl Lewis X determinants that serve as recognition epitopes for C-type lectins. Together with FUT7 contributes to SELE, SELL and SELP selectin ligand biosynthesis and selectin-dependent lymphocyte homing, leukocyte migration and blood leukocyte homeostasis. In a cell type specific manner, may also fucosylate the internal LacNAc unit of the polylactosamine chain to form VIM-2 antigen that serves as recognition epitope for SELE. Isoform Long: Does not generate Lewis X antigens.
Protein Name	Alpha-(1 -3-Fucosyltransferase 4 4-Galactosyl-N-Acetylglucosaminide 3-Alpha-L-Fucosyltransferase Elam-1 Ligand Fucosyltransferase Fucosyltransferase 4 Fucosyltransferase Iv Fuc-Tiv Fuct-Iv Galactoside 3-L-Fucosyltransferase
Database Links	Reactome: R-HSA-9037629
Cellular Localisation	Golgi Apparatus Golgi Stack Membrane Single-Pass Type Ii Membrane Protein Membrane-Bound Form In Trans Cisternae Of Golgi
Alternative ELISA Names	Alpha-(1 -3-Fucosyltransferase 4 ELISA kit 4-Galactosyl-N-Acetylglucosaminide 3-Alpha-L-Fucosyltransferase ELISA kit Elam-1 Ligand Fucosyltransferase ELISA kit Fucosyltransferase 4 ELISA kit Fucosyltransferase Iv ELISA kit Fuc-Tiv ELISA kit Fuct-Iv ELISA kit Galactoside 3-L-Fucosyltransferase ELISA kit FUT4 ELISA kit ELFT ELISA kit FCT3A ELISA kit
output

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance

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Human FUT4 (Fucosyltransferase 4) Sandwich ELISA Kit Ready-To-Use (STJE0015388)