Human GAN (Gigaxonin) Sandwich ELISA Kit (STJE0009075) STJE0009075 上海玉博生物科技有限公司

Human GAN (Gigaxonin) Sandwich ELISA Kit (STJE0009075)

简单介绍

Human GAN (Gigaxonin) Sandwich ELISA Kit (STJE0009075)

产品描述

Applications:	ELISA
Reactivity:	Human
Note:	STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Sensitivity:	0.055ng/mL
Detection Limit:	0.156-10ng/mL
Short Description:	This GAN Sandwich ELISA Kit is an in-vitro enzyme-linked immunosorbent assay for the measurement of samples in human cell culture supernatant, serum and plasma (EDTA, citrate, heparin).

Storage Instruction:	Store the unopened kit in the fridge at 2-8°C for up to 6 months. Once opened store individual kit contents according to components table provided with the kit.
Assay Time:	4.5 hrs

Gene Symbol:	GAN
Gene ID:	8139
Uniprot ID:	GAN_HUMAN
Sample Type:	tissue homogenates or other biological fluids.

Tissue Specificity	Expressed in brain, heart and muscle.
Post Translational Modifications	Ubiquitinated by E3 ubiquitin ligase complex formed by CUL3 and RBX1 and probably targeted for proteasome-independent degradation.
Function	Probable cytoskeletal component that directly or indirectly plays an important role in neurofilament architecture. May act as a substrate-specific adapter of an E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins. Controls degradation of TBCB. Controls degradation of MAP1B and MAP1S, and is critical for neuronal maintenance and survival.
Protein Name	Gigaxonin Kelch-Like Protein 16
Database Links	Reactome: R-HSA-8951664 Reactome: R-HSA-983168
Cellular Localisation	Cytoplasm Cytoskeleton
Alternative ELISA Names	Gigaxonin ELISA kit Kelch-Like Protein 16 ELISA kit GAN ELISA kit GAN1 ELISA kit KLHL16 ELISA kit
output

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance

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