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> Human HTR2A (5-Hydroxytryptamine Receptor 2A) Sandwich ELISA Kit Ready-To-Use (STJE0015980)

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Human HTR2A (5-Hydroxytryptamine Receptor 2A) Sandwich ELISA Kit Ready-To-Use (STJE0015980)

Human HTR2A (5-Hydroxytryptamine Receptor 2A) Sandwich ELISA Kit Ready-To-Use (STJE0015980)
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  • 产品名称:Human HTR2A (5-Hydroxytryptamine Receptor 2A) Sandwich ELISA Kit Ready-To-Use (STJE0015980)
  • 产品型号:STJE0015980
  • 产品展商:ST john's laboratory
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简单介绍
Human HTR2A (5-Hydroxytryptamine Receptor 2A) Sandwich ELISA Kit Ready-To-Use (STJE0015980)
产品描述
Applications: ELISA
Reactivity: Human
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Sensitivity: 0.057ng/mL
Detection Limit: 0.156-10ng/mL
Short Description: This HTR2A Sandwich ELISA Kit, Ready-To-Use is an in-vitro enzyme-linked immunosorbent assay for the measurement of samples in human cell culture supernatant, serum and plasma (EDTA, citrate, heparin).
Storage Instruction: The whole kit may be stored at-20°C for up to 12 months from receipt. An unopened kit may be stored in the fridge at 2-8°C for up to 6 months. Once opened store individual kit contents according to components table provided with the kit.
Assay Time: 3 hrs
Gene Symbol: HTR2A
Gene ID: 3356
Uniprot ID: 5HT2A_HUMAN
Immunogen Region: Ready-To-Use
Sample Type: tissue homogenates, cell lysates or other biological fluids.
Tissue Specificity Detected in brain cortex (at protein level). Detected in blood platelets.
Post Translational Modifications
Function G-protein coupled receptor for 5-hydroxytryptamine (serotonin). Also functions as a receptor for various drugs and psychoactive substances, including mescaline, psilocybin, 1-(2,5-dimethoxy-4-iodophenyl)-2-aminopropane (DOI) and lysergic acid diethylamide (LSD). Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors. Beta-arrestin family members inhibit signaling via G proteins and mediate activation of alternative signaling pathways. Signaling activates phospholipase C and a phosphatidylinositol-calcium second messenger system that modulates the activity of phosphatidylinositol 3-kinase and promotes the release of Ca(2+) ions from intracellular stores. Affects neural activity, perception, cognition and mood. Plays a role in the regulation of behavior, including responses to anxiogenic situations and psychoactive substances. Plays a role in intestinal smooth muscle contraction, and may play a role in arterial vasoconstriction. (Microbial infection) Acts as a receptor for human JC polyomavirus/JCPyV.
Protein Name 5-Hydroxytryptamine Receptor 2a
5-Ht-2
5-Ht-2a
Serotonin Receptor 2a
Database Links Reactome: R-HSA-390666
Reactome: R-HSA-416476
Cellular Localisation Cell Membrane
Multi-Pass Membrane Protein
Cell Projection
Dendrite
Axon
Cytoplasmic Vesicle
Membrane
Caveola
Presynapse
Alternative ELISA Names 5-Hydroxytryptamine Receptor 2a ELISA kit
5-Ht-2 ELISA kit
5-Ht-2a ELISA kit
Serotonin Receptor 2a ELISA kit
HTR2A ELISA kit
HTR2 ELISA kit
output

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
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