Human HTR2C (5-Hydroxytryptamine Receptor 2C) Sandwich ELISA Kit Ready-To-Use (STJE0015982) STJE0015982 上海玉博生物科技有限公司

Human HTR2C (5-Hydroxytryptamine Receptor 2C) Sandwich ELISA Kit Ready-To-Use (STJE0015982)

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产品名称：Human HTR2C (5-Hydroxytryptamine Receptor 2C) Sandwich ELISA Kit Ready-To-Use (STJE0015982)
产品型号：STJE0015982
产品展商：ST john's laboratory
产品文档：无相关文档

简单介绍

Human HTR2C (5-Hydroxytryptamine Receptor 2C) Sandwich ELISA Kit Ready-To-Use (STJE0015982)

产品描述

Applications:	ELISA
Reactivity:	Human
Note:	STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Sensitivity:	0.064ng/mL
Detection Limit:	0.156-10ng/mL
Short Description:	This HTR2C Sandwich ELISA Kit, Ready-To-Use is an in-vitro enzyme-linked immunosorbent assay for the measurement of samples in human cell culture supernatant, serum and plasma (EDTA, citrate, heparin).

Storage Instruction:	The whole kit may be stored at-20°C for up to 12 months from receipt. An unopened kit may be stored in the fridge at 2-8°C for up to 6 months. Once opened store individual kit contents according to components table provided with the kit.
Assay Time:	3 hrs

Gene Symbol:	HTR2C
Gene ID:	3358
Uniprot ID:	5HT2C_HUMAN
Immunogen Region:	Ready-To-Use
Sample Type:	tissue homogenates or other biological fluids.

Tissue Specificity	Detected in brain.
Post Translational Modifications	N-glycosylated.
Function	G-protein coupled receptor for 5-hydroxytryptamine (serotonin). Also functions as a receptor for various drugs and psychoactive substances, including ergot alkaloid derivatives, 1-2,5,-dimethoxy-4-iodophenyl-2-aminopropane (DOI) and lysergic acid diethylamide (LSD). Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors. Beta-arrestin family members inhibit signaling via G proteins and mediate activation of alternative signaling pathways. Signaling activates a phosphatidylinositol-calcium second messenger system that modulates the activity of phosphatidylinositol 3-kinase and down-stream signaling cascades and promotes the release of Ca(2+) ions from intracellular stores. Regulates neuronal activity via the activation of short transient receptor potential calcium channels in the brain, and thereby modulates the activation of pro-opiomelacortin neurons and the release of CRH that then regulates the release of corticosterone. Plays a role in the regulation of appetite and eating behavior, responses to anxiogenic stimuli and stress. Plays a role in insulin sensitivity and glucose homeostasis.
Protein Name	5-Hydroxytryptamine Receptor 2c 5-Ht-2c 5-Ht2c 5-Htr2c 5-Hydroxytryptamine Receptor 1c 5-Ht-1c 5-Ht1c Serotonin Receptor 2c
Database Links	Reactome: R-HSA-390666 Reactome: R-HSA-416476
Cellular Localisation	Cell Membrane Multi-Pass Membrane Protein
Alternative ELISA Names	5-Hydroxytryptamine Receptor 2c ELISA kit 5-Ht-2c ELISA kit 5-Ht2c ELISA kit 5-Htr2c ELISA kit 5-Hydroxytryptamine Receptor 1c ELISA kit 5-Ht-1c ELISA kit 5-Ht1c ELISA kit Serotonin Receptor 2c ELISA kit HTR2C ELISA kit HTR1C ELISA kit
output

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance

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Human HTR2C (5-Hydroxytryptamine Receptor 2C) Sandwich ELISA Kit Ready-To-Use (STJE0015982)