Human IL12Rb2 (Interleukin 12 Receptor Beta 2) Sandwich ELISA Kit (STJE0009774) STJE0009774 上海玉博生物科技有限公司

Human IL12Rb2 (Interleukin 12 Receptor Beta 2) Sandwich ELISA Kit (STJE0009774)

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产品名称：Human IL12Rb2 (Interleukin 12 Receptor Beta 2) Sandwich ELISA Kit (STJE0009774)
产品型号：STJE0009774
产品展商：ST john's laboratory
产品文档：无相关文档

简单介绍

Human IL12Rb2 (Interleukin 12 Receptor Beta 2) Sandwich ELISA Kit (STJE0009774)

产品描述

Applications:	ELISA
Reactivity:	Human
Note:	STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Sensitivity:	0.055ng/mL
Detection Limit:	0.156-10ng/mL
Short Description:	This IL12Rb2 Sandwich ELISA Kit is an in-vitro enzyme-linked immunosorbent assay for the measurement of samples in human cell culture supernatant, serum and plasma (EDTA, citrate, heparin).

Storage Instruction:	Store the unopened kit in the fridge at 2-8°C for up to 6 months. Once opened store individual kit contents according to components table provided with the kit.
Assay Time:	4.5 hrs

Gene Symbol:	IL12RB2
Gene ID:	3595
Uniprot ID:	I12R2_HUMAN
Sample Type:	serum, plasma, tissue homogenates or other biological fluids.

Tissue Specificity	Isoform 2 is expressed at similar levels in both naive and activated T-cells.
Post Translational Modifications	On IL12 binding, phosphorylated on C-terminal tyrosine residues by JAK2. Phosphorylation on Tyr-800 is required for STAT4 binding and activation, and for SOCS3 binding.
Function	Receptor for interleukin-12. This subunit is the signaling component coupling to the JAK2/STAT4 pathway. Promotes the proliferation of T-cells as well as NK cells. Induces the promotion of T-cells towards the Th1 phenotype by strongly enhancing IFN-gamma production.
Protein Name	Interleukin-12 Receptor Subunit Beta-2 Il-12 Receptor Subunit Beta-2 Il-12r Subunit Beta-2 Il-12r-Beta-2 Il-12rb2
Database Links	Reactome: R-HSA-8984722 Reactome: R-HSA-9020591
Cellular Localisation	Membrane Single-Pass Type I Membrane Protein
Alternative ELISA Names	Interleukin-12 Receptor Subunit Beta-2 ELISA kit Il-12 Receptor Subunit Beta-2 ELISA kit Il-12r Subunit Beta-2 ELISA kit Il-12r-Beta-2 ELISA kit Il-12rb2 ELISA kit IL12RB2 ELISA kit
output

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance

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