Human IL13 (IL13) Sandwich ELISA Kit (STJE0000022) STJE0000022-96 上海玉博生物科技有限公司

Human IL13 (IL13) Sandwich ELISA Kit (STJE0000022)

简单介绍

Human IL13 (IL13) Sandwich ELISA Kit (STJE0000022)

产品描述

Applications:	ELISA
Reactivity:	Human
Note:	STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Sensitivity:	23 pg/mL
Detection Limit:	469-3000 pg/ml
Short Description:	This IL13 Sandwich ELISA Kit is an in-vitro enzyme-linked immunosorbent assay for the measurement of samples in human cell culture supernatant, serum and plasma (EDTA, citrate, heparin).

Conjugation:	Biotin
Storage Instruction:	Unopened kits can be stored at 2-8°C for 1 year, and opened products must be used within 1 month.
Assay Time:	4 hours
Detection:	Colorimetric

Gene Symbol:	IL13
Gene ID:	3596
Uniprot ID:	IL13_HUMAN
Sample Type:	serum, plasma and cell culture supernates

Tissue Specificity
Post Translational Modifications
Function	Cytokine that plays important roles in allergic inflammation and immune response to parasite infection. Synergizes with IL2 in regulating interferon-gamma synthesis. Stimulates B-cell proliferation, and activation of eosinophils, basophils, and mast cells. Plays an important role in controlling IL33 activity by modulating the production of transmembrane and soluble forms of interleukin-1 receptor-like 1/IL1RL1. Displays the capacity to antagonize Th1-driven proinflammatory immune response and downregulates synthesis of many proinflammatory cytokines including IL1, IL6, IL10, IL12 and TNF-alpha through a mechanism that partially involves suppression of NF-kappa-B. Functions also on nonhematopoietic cells, including endothelial cells where it induces vascular cell adhesion protein 1/VCAM1, which is important in the recruitment of eosinophils. Exerts its biological effects through its receptors which comprises the IL4R chain and the IL13RA1 chain, to activate JAK1 and TYK2, leading to the activation of STAT6. Aside from IL13RA1, another receptor IL13RA2 acts as a high affinity decoy for IL13 and mediates internalization and depletion of extracellular IL13.
Protein Name	Interleukin-13 Il-13
Database Links	Reactome: R-HSA-6785807 Reactome: R-HSA-9012546
Cellular Localisation	Secreted
Alternative ELISA Names	Interleukin-13 ELISA kit Il-13 ELISA kit IL13 ELISA kit NC30 ELISA kit
output

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance

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