Human IL15 (Interleukin 15) Sandwich ELISA Kit (STJE0007081) STJE0007081 上海玉博生物科技有限公司

Human IL15 (Interleukin 15) Sandwich ELISA Kit (STJE0007081)

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产品名称：Human IL15 (Interleukin 15) Sandwich ELISA Kit (STJE0007081)
产品型号：STJE0007081
产品展商：ST john's laboratory
产品文档：无相关文档

简单介绍

Human IL15 (Interleukin 15) Sandwich ELISA Kit (STJE0007081)

产品描述

Applications:	ELISA
Reactivity:	Human
Note:	STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Sensitivity:	6.8pg/mL
Detection Limit:	15.6-1000pg/mL
Short Description:	This IL15 Sandwich ELISA Kit is an in-vitro enzyme-linked immunosorbent assay for the measurement of samples in human cell culture supernatant, serum and plasma (EDTA, citrate, heparin).

Storage Instruction:	Store the unopened kit in the fridge at 2-8°C for up to 6 months. Once opened store individual kit contents according to components table provided with the kit.
Assay Time:	4.5 hrs

Gene Symbol:	IL15
Gene ID:	3600
Uniprot ID:	IL15_HUMAN
Sample Type:	serum, plasma, tissue homogenates, cell lysates, cell culture supernates or other biological fluids.

Tissue Specificity	Most abundant in placenta and skeletal muscle. It is also detected in the heart, lung, liver and kidney. IL15-S21AA is preferentially expressed in tissues such as testis and thymus.
Post Translational Modifications
Function	Cytokine that plays a major role in the development of inflammatory and protective immune responses to microbial invaders and parasites by modulating immune cells of both the innate and adaptive immune systems. Stimulates the proliferation of natural killer cells, T-cells and B-cells and promotes the secretion of several cytokines. In monocytes, induces the production of IL8 and monocyte chemotactic protein 1/CCL2, two chemokines that attract neutrophils and monocytes respectively to sites of infection. Unlike most cytokines, which are secreted in soluble form, IL15 is expressed in association with its high affinity IL15RA on the surface of IL15-producing cells and delivers signals to target cells that express IL2RB and IL2RG receptor subunits. Binding to its receptor triggers the phosphorylation of JAK1 and JAK3 and the recruitment and subsequent phosphorylation of signal transducer and activator of transcription-3/STAT3 and STAT5. In mast cells, induces the rapid tyrosine phosphorylation of STAT6 and thereby controls mast cell survival and release of cytokines such as IL4.
Protein Name	Interleukin-15 Il-15
Database Links	Reactome: R-HSA-8983432
Cellular Localisation	Isoform Il15-S48aa: Secreted Isoform Il15-S21aa: Cytoplasm Nucleus Il15-S21aa Is Not Secreted But Rather Is Stored Intracellularly Appearing In The Nucleus And Cytoplasmic Components
Alternative ELISA Names	Interleukin-15 ELISA kit Il-15 ELISA kit IL15 ELISA kit
output

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance

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Human IL15 (Interleukin 15) Sandwich ELISA Kit (STJE0007081)