Human IL1R2 (Interleukin-1 receptor type 2) CLIA Kit (STJC0000083) STJC0000083 上海玉博生物科技有限公司

Human IL1R2 (Interleukin-1 receptor type 2) CLIA Kit (STJC0000083)

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产品名称：Human IL1R2 (Interleukin-1 receptor type 2) CLIA Kit (STJC0000083)
产品型号：STJC0000083
产品展商：ST john's laboratory
产品文档：无相关文档

简单介绍

Human IL1R2 (Interleukin-1 receptor type 2) CLIA Kit (STJC0000083)

产品描述

Applications:	CLIA
Reactivity:	Human
Note:	FOR SCIENTIFIC EDUCATIONAL RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR OTHER MEDICAL APPLICATIONS.
Sensitivity:	7.5pg/mL
Detection Limit:	12.5~800pg/mL
Short Description:	This human IL1R2 kit is a highly sensitive in-vitro chemiluminescent immunoassay for the measurement of trace amounts of analytes.

Storage Instruction:	If unopened the kit may be stored at 2-8°C for up to 1 month. If the kit will not be used within 1 month, store the components separately, according to the component table in the manual.
Assay Time:	3.5h
Detection:	Chemiluminescence

Gene Symbol:	IL1R2
Gene ID:	7850
Uniprot ID:	IL1R2_HUMAN
Specificity:	This kit recognizes Human IL-1R2 in samples. No significant cross-reactivity or interference between Human IL-1R2 and analogues was observed.
Sample Type:	Serum, plasma and other biological fluids

Post Translational Modifications	A soluble form (sIL1R2) can also be produced by proteolytic cleavage at the cell surface (shedding) involving a metalloproteinase.hovever, several sIL1R2 forms ranging from 45 and 60 kDa are reported.
Function	Non-signaling receptor for IL1A, IL1B and IL1RN. Reduces IL1B activities. Serves as a decoy receptor by competitive binding to IL1B and preventing its binding to IL1R1. Also modulates cellular response through non-signaling association with IL1RAP after binding to IL1B. IL1R2 (membrane and secreted forms) preferentially binds IL1B and poorly IL1A and IL1RN. The secreted IL1R2 recruits secreted IL1RAP with high affinity.this complex formation may be the dominant mechanism for neutralization of IL1B by secreted/soluble receptors.
Protein Name	Interleukin-1 Receptor Type 2 Il-1r-2 Il-1rt-2 Il-1rt2 Cd121 Antigen-Like Family Member B Cdw121b Il-1 Type Ii Receptor Interleukin-1 Receptor Beta Il-1r-Beta Interleukin-1 Receptor Type Ii Cd Antigen Cd121b Cleaved Into - Interleukin-1 Receptor Type 2 - Membrane Form Mil-1r2 Mil-1rii - Interleukin-1 Receptor Type 2 - Soluble Form Sil-1r2 Sil-1rii
Database Links	Reactome: R-HSA-6783783 Reactome: R-HSA-9020702
Cellular Localisation	Isoform Short: Secreted Isoform Long: Cell Membrane Single-Pass Type I Membrane Protein
Alternative CLIA Names	Interleukin-1 Receptor Type 2 CLIA kit Il-1r-2 CLIA kit Il-1rt-2 CLIA kit Il-1rt2 CLIA kit Cd121 Antigen-Like Family Member B CLIA kit Cdw121b CLIA kit Il-1 Type Ii Receptor CLIA kit Interleukin-1 Receptor Beta CLIA kit Il-1r-Beta CLIA kit Interleukin-1 Receptor Type Ii CLIA kit Cd Antigen Cd121b Cleaved Into - Interleukin-1 Receptor Type 2 - Membrane Form CLIA kit Mil-1r2 CLIA kit Mil-1rii - Interleukin-1 Receptor Type 2 - Soluble Form CLIA kit Sil-1r2 CLIA kit Sil-1rii CLIA kit IL1R2 CLIA kit IL1RB CLIA kit
Specificity	This kit recognizes Human IL-1R2 in samples. No significant cross-reactivity or interference between Human IL-1R2 and analogues was observed.
Reproducibility	Both intra-CV and inter-CV are

Information sourced from Uniprot.org

Item Specifications Storage

Micro CLIA Plate (Dismountable)	96T: 8 wells ×12 strips strips	-20℃, 6 months
Reference Standard	96T: 2 vials 48T: 1 vial	-20℃, 6 months
Concentrated Biotinylated Detection Ab (100×)	96T: 1 vial, 120 μL 60 μL	-20℃, 6 months
Concentrated HRP Conjugate (100×)	96T: 1 vial, 120 μL 60 μL	-20℃ (Protect from light), 6 months
Reference Standard & Sample Diluent	1 vial, 20 mL	2-8°C, 6 months
Biotinylated Detection Ab Diluent	1 vial, 14 mL	2-8°C, 6 months
HRP Conjugate Diluent	1 vial, 14 mL	2-8°C, 6 months
Concentrated Wash Buffer (25×)	1 vial, 30 mL	2-8°C, 6 months
Substrate Reagent A	1 vial, 5 mL	2-8℃ (Protect from light)
Substrate Reagent B	1 vial, 5 mL	2-8℃ (Protect from light)
Plate Sealer	5 pieces
Manual	1 copy
Certificate of Analysis	1 copy

Sample Type Range (%) Average Recovery (%)

Serum(n=8)	94-111	101
EDTA plasma(n=8)	85-96	91
Cell culture media(n=8)	97-115	105

Intra-assay Precision Intra-assay Precision Intra-assay Precision Inter-assay Precision Inter-assay Precision Inter-assay Precision

Sample	1.00	2.00	3.00	1.00	2.00	3.00
n	20.00	20.00	20.00	20.00	20.00	20.00
Mean (pg/mL)	37.51	100.85	343.93	35.46	100.29	361.66
Standard deviation	3.04	9.33	32.85	4.32	10.38	29.48
CV (%)	8.10	9.25	9.55	12.18	10.35	8.15

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance

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Human IL1R2 (Interleukin-1 receptor type 2) CLIA Kit (STJC0000083)