Anti-C1QA antibody (23-245) (STJ26180) STJ26180 上海玉博生物科技有限公司

Anti-C1QA antibody (23-245) (STJ26180)

简单介绍

Anti-C1QA antibody (23-245) (STJ26180)

产品描述

Host:	Rabbit
Applications:	WB
Reactivity:	Human/Mouse/Rat
Note:	STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description:	Rabbit polyclonal antibody anti-C1QA (23-245) is suitable for use in Western Blot research applications.

Clonality:	Polyclonal
Conjugation:	Unconjugated
Isotype:	IgG
Formulation:	PBS with 0.05% Proclin300, 50% Glycerol, pH7.3.
Purification:	Affinity purification
Dilution Range:	WB 1:500-1:2000
Storage Instruction:	Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.

Gene Symbol:	C1QA
Gene ID:	712
Uniprot ID:	C1QA_HUMAN
Immunogen Region:	23-245
Immunogen:	Recombinant fusion protein containing a sequence corresponding to amino acids 23-245 of human C1QA (NP_001334394.1).
Immunogen Sequence:	EDLCRAPDGKKGEAGRPGRR GRPGLKGEQGEPGAPGIRTG IQGLKGDQGEPGPSGNPGKV GYPGPSGPLGARGIPGIKGT KGSPGNIKDQPRPAFSAIRR NPPMGGNVVIFDTVITNQEE PYQNHSGRFVCTVPGYYYFT FQVLSQWEICLSIVSSSRGQ VRRSLGFCDTTNKGLFQVVS GGMVLQLQQGDQVWVEKDPK KGHIYQGSEADSVFSGFLIF PSA

Post Translational Modifications	O-linked glycans are assumed to be the Glc-Gal disaccharides typically found as secondary modifications of hydroxylated lysines in collagen-like domains.
Function	C1q associates with the proenzymes C1r and C1s to yield C1, the first component of the serum complement system. The collagen-like regions of C1q interact with the Ca(2+)-dependent C1r(2)C1s(2) proenzyme complex, and efficient activation of C1 takes place on interaction of the globular heads of C1q with the Fc regions of IgG or IgM antibody present in immune complexes.
Protein Name	Complement C1q Subcomponent Subunit A
Database Links	Reactome: R-HSA-166663 Reactome: R-HSA-173623 Reactome: R-HSA-977606
Cellular Localisation	Secreted
Alternative Antibody Names	Anti-Complement C1q Subcomponent Subunit A antibody Anti-C1QA antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance

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