Human GRIA3 (Glutamate Receptor, Ionotropic, AMPA 3) Sandwich ELISA Kit Ready-To-Use (STJE0015676) STJE0015676 上海玉博生物科技有限公司

Human GRIA3 (Glutamate Receptor, Ionotropic, AMPA 3) Sandwich ELISA Kit Ready-To-Use (STJE0015676)

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产品名称：Human GRIA3 (Glutamate Receptor, Ionotropic, AMPA 3) Sandwich ELISA Kit Ready-To-Use (STJE0015676)
产品型号：STJE0015676
产品展商：ST john's laboratory
产品文档：无相关文档

简单介绍

Human GRIA3 (Glutamate Receptor, Ionotropic, AMPA 3) Sandwich ELISA Kit Ready-To-Use (STJE0015676)

产品描述

Applications:	ELISA
Reactivity:	Human
Note:	STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Sensitivity:	0.116ng/mL
Detection Limit:	0.312-20ng/mL
Short Description:	This GRIA3 Sandwich ELISA Kit, Ready-To-Use is an in-vitro enzyme-linked immunosorbent assay for the measurement of samples in human cell culture supernatant, serum and plasma (EDTA, citrate, heparin).

Storage Instruction:	The whole kit may be stored at-20°C for up to 12 months from receipt. An unopened kit may be stored in the fridge at 2-8°C for up to 6 months. Once opened store individual kit contents according to components table provided with the kit.
Assay Time:	3 hrs

Gene Symbol:	GRIA3
Gene ID:	2892
Uniprot ID:	GRIA3_HUMAN
Immunogen Region:	Ready-To-Use
Sample Type:	tissue homogenates or other biological fluids.

Tissue Specificity
Post Translational Modifications	Palmitoylated. Depalmitoylated upon glutamate stimulation. Cys-621 palmitoylation leads to Golgi retention and decreased cell surface expression. In contrast, Cys-847 palmitoylation does not affect cell surface expression but regulates stimulation-dependent endocytosis.
Function	Receptor for glutamate that functions as ligand-gated ion channel in the central nervous system and plays an important role in excitatory synaptic transmission. L-glutamate acts as an excitatory neurotransmitter at many synapses in the central nervous system. Binding of the excitatory neurotransmitter L-glutamate induces a conformation change, leading to the opening of the cation channel, and thereby converts the chemical signal to an electrical impulse. The receptor then desensitizes rapidly and enters a transient inactive state, characterized by the presence of bound agonist. In the presence of CACNG4 or CACNG7 or CACNG8, shows resensitization which is characterized by a delayed accumulation of current flux upon continued application of glutamate.
Protein Name	Glutamate Receptor 3 Glur-3 Ampa-Selective Glutamate Receptor 3 Glur-C Glur-K3 Glutamate Receptor Ionotropic - Ampa 3 Glua3
Database Links	Reactome: R-HSA-399710 Reactome: R-HSA-399719 Reactome: R-HSA-416993 Reactome: R-HSA-438066 Reactome: R-HSA-8849932
Cellular Localisation	Cell Membrane Multi-Pass Membrane Protein Postsynaptic Cell Membrane Interaction With Cnih2 And Cnih3 Promotes Cell Surface Expression
Alternative ELISA Names	Glutamate Receptor 3 ELISA kit Glur-3 ELISA kit Ampa-Selective Glutamate Receptor 3 ELISA kit Glur-C ELISA kit Glur-K3 ELISA kit Glutamate Receptor Ionotropic - Ampa 3 ELISA kit Glua3 ELISA kit GRIA3 ELISA kit GLUR3 ELISA kit GLURC ELISA kit
output

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance

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Human GRIA3 (Glutamate Receptor, Ionotropic, AMPA 3) Sandwich ELISA Kit Ready-To-Use (STJE0015676)