Anti-CA2 antibody (1-250) (STJ11100007) STJ11100007 上海玉博生物科技有限公司

Anti-CA2 antibody (1-250) (STJ11100007)

简单介绍

Anti-CA2 antibody (1-250) (STJ11100007)

产品描述

Host:	Rabbit
Applications:	WB
Reactivity:	Human/Mouse
Note:	STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description:	Rabbit polyclonal antibody anti-CA2 (1-250) is suitable for use in Western Blot research applications.

Clonality:	Polyclonal
Conjugation:	Unconjugated
Isotype:	IgG
Formulation:	PBS with 0.01% Thimerosal, 50% Glycerol, pH7.3.
Purification:	Affinity purification
Dilution Range:	WB 1:500-1:2000
Storage Instruction:	Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.

Gene Symbol:	CA2
Gene ID:	760
Uniprot ID:	CAH2_HUMAN
Immunogen Region:	1-250
Immunogen:	Recombinant fusion protein containing a sequence corresponding to amino acids 1-250 of human Carbonic Anhydrase 2 (CA2) (NP_000058.1).
Immunogen Sequence:	MSHHWGYGKHNGPEHWHKDF PIAKGERQSPVDIDTHTAKY DPSLKPLSVSYDQATSLRIL NNGHAFNVEFDDSQDKAVLK GGPLDGTYRLIQFHFHWGSL DGQGSEHTVDKKKYAAELHL VHWNTKYGDFGKAVQQPDGL AVLGIFLKVGSAKPGLQKVV DVLDSIKTKGKSADFTNFDP RGLLPESLDYWTYPGSLTTP PLLECVTWIVLKEPISVSSE QVLKFRKLNFNGEGEPEEL

Function	Catalyzes the reversible hydration of carbon dioxide. Can also hydrate cyanamide to urea. Stimulates the chloride-bicarbonate exchange activity of SLC26A6. Essential for bone resorption and osteoclast differentiation. Involved in the regulation of fluid secretion into the anterior chamber of the eye. Contributes to intracellular pH regulation in the duodenal upper villous epithelium during proton-coupled peptide absorption.
Protein Name	Carbonic Anhydrase 2 Carbonate Dehydratase Ii Carbonic Anhydrase C Cac Carbonic Anhydrase Ii Ca-Ii Cyanamide Hydratase Ca2
Database Links	Reactome: R-HSA-1237044 Reactome: R-HSA-1247673 Reactome: R-HSA-1475029
Cellular Localisation	Cytoplasm Cell Membrane Colocalized With Slc26a6 At The Surface Of The Cell Membrane In Order To Form A Bicarbonate Transport Metabolon Displaced From The Cytosolic Surface Of The Cell Membrane By Pkc In Phorbol Myristate Acetate (Pma)-Induced Cells
Alternative Antibody Names	Anti-Carbonic Anhydrase 2 antibody Anti-Carbonate Dehydratase Ii antibody Anti-Carbonic Anhydrase C antibody Anti-Cac antibody Anti-Carbonic Anhydrase Ii antibody Anti-Ca-Ii antibody Anti-Cyanamide Hydratase Ca2 antibody Anti-CA2 antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance

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