Human HEXa (Hexosaminidase A Alpha) Sandwich ELISA Kit (STJE0009437) STJE0009437 上海玉博生物科技有限公司

Human HEXa (Hexosaminidase A Alpha) Sandwich ELISA Kit (STJE0009437)

简单介绍

Human HEXa (Hexosaminidase A Alpha) Sandwich ELISA Kit (STJE0009437)

产品描述

Applications:	ELISA
Reactivity:	Human
Note:	STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Sensitivity:	0.059ng/mL
Detection Limit:	0.156-10ng/mL
Short Description:	This HEXa Sandwich ELISA Kit is an in-vitro enzyme-linked immunosorbent assay for the measurement of samples in human cell culture supernatant, serum and plasma (EDTA, citrate, heparin).

Storage Instruction:	Store the unopened kit in the fridge at 2-8°C for up to 6 months. Once opened store individual kit contents according to components table provided with the kit.
Assay Time:	4.5 hrs

Gene Symbol:	HEXA
Gene ID:	3073
Uniprot ID:	HEXA_HUMAN
Sample Type:	serum, plasma, tissue homogenates or other biological fluids.

Tissue Specificity
Post Translational Modifications	N-linked glycan at Asn-115 consists of Man(3)-GlcNAc(2) (Probable). N-linked glycan at Asn-157 consists of either GlcNAc or GlcNAc(2)-Man(7-9). N-linked glycan at Asn-295 consists of either GlcNAc, GlcNAc-Fuc, or GlcNAc(2)-Man(4) (Probable).
Function	Hydrolyzes the non-reducing end N-acetyl-D-hexosamine and/or sulfated N-acetyl-D-hexosamine of glycoconjugates, such as the oligosaccharide moieties from proteins and neutral glycolipids, or from certain mucopolysaccharides. The isozyme S is as active as the isozyme A on the anionic bis-sulfated glycans, the chondroitin-6-sulfate trisaccharide (C6S-3), and the dermatan sulfate pentasaccharide, and the sulfated glycosphingolipid SM2. The isozyme B does not hydrolyze each of these substrates, however hydrolyzes efficiently neutral oligosaccharide. Only the isozyme A is responsible for the degradation of GM2 gangliosides in the presence of GM2A.
Protein Name	Beta-Hexosaminidase Subunit Alpha Beta-N-Acetylhexosaminidase Subunit Alpha Hexosaminidase Subunit A N-Acetyl-Beta-Glucosaminidase Subunit Alpha
Database Links	Reactome: R-HSA-1660662 Reactome: R-HSA-2022857 Reactome: R-HSA-2024101 Reactome: R-HSA-2160916 Reactome: R-HSA-3656234
Cellular Localisation	Lysosome
Alternative ELISA Names	Beta-Hexosaminidase Subunit Alpha ELISA kit Beta-N-Acetylhexosaminidase Subunit Alpha ELISA kit Hexosaminidase Subunit A ELISA kit N-Acetyl-Beta-Glucosaminidase Subunit Alpha ELISA kit HEXA ELISA kit
output

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance

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