Anti-CACNG2 antibody (204-323) (STJ116036) STJ116036 上海玉博生物科技有限公司

Anti-CACNG2 antibody (204-323) (STJ116036)

简单介绍

Anti-CACNG2 antibody (204-323) (STJ116036)

产品描述

Host:	Rabbit
Applications:	IF
Reactivity:	Human
Note:	STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description:	Rabbit polyclonal antibody anti-CACNG2 (204-323) is suitable for use in Immunofluorescence research applications.

Clonality:	Polyclonal
Conjugation:	Unconjugated
Isotype:	IgG
Formulation:	PBS with 0.02% Sodium Azide, 50% Glycerol, pH7.3.
Purification:	Affinity purification
Dilution Range:	IF 1:50-1:100
Storage Instruction:	Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.

Gene Symbol:	CACNG2
Gene ID:	10369
Uniprot ID:	CCG2_HUMAN
Immunogen Region:	204-323
Immunogen:	Recombinant fusion protein containing a sequence corresponding to amino acids 204-323 of human CACNG2 (NP_006069.1).
Immunogen Sequence:	RHKQLRATARATDYLQASAI TRIPSYRYRYQRRSRSSSRS TEPSHSRDASPVGIKGFNTL PSTEISMYTLSRDPLKAATT PTATYNSDRDNSFLQVHNCI QKENKDSLHSNTANRRTTPV

Tissue Specificity	Brain.
Post Translational Modifications	Phosphorylation of Thr-321 impairs interaction with DLG1 and DLG4.
Function	Regulates the trafficking and gating properties of AMPA-selective glutamate receptors (AMPARs). Promotes their targeting to the cell membrane and synapses and modulates their gating properties by slowing their rates of activation, deactivation and desensitization. Does not show subunit-specific AMPA receptor regulation and regulates all AMPAR subunits. Thought to stabilize the calcium channel in an inactivated (closed) state.
Protein Name	Voltage-Dependent Calcium Channel Gamma-2 Subunit Neuronal Voltage-Gated Calcium Channel Gamma-2 Subunit Transmembrane Ampar Regulatory Protein Gamma-2 Tarp Gamma-2
Database Links	Reactome: R-HSA-112308 Reactome: R-HSA-399719 Reactome: R-HSA-5682910
Cellular Localisation	Membrane Multi-Pass Membrane Protein Synapse Synaptosome
Alternative Antibody Names	Anti-Voltage-Dependent Calcium Channel Gamma-2 Subunit antibody Anti-Neuronal Voltage-Gated Calcium Channel Gamma-2 Subunit antibody Anti-Transmembrane Ampar Regulatory Protein Gamma-2 antibody Anti-Tarp Gamma-2 antibody Anti-CACNG2 antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance

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