Human Hpt (Haptoglobin) Sandwich ELISA Kit Ready-To-Use (STJE0006935) STJE0006935 上海玉博生物科技有限公司

Human Hpt (Haptoglobin) Sandwich ELISA Kit Ready-To-Use (STJE0006935)

简单介绍

Human Hpt (Haptoglobin) Sandwich ELISA Kit Ready-To-Use (STJE0006935)

产品描述

Applications:	ELISA
Reactivity:	Human
Note:	STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Sensitivity:	0.058ng/mL
Detection Limit:	0.156-10ng/mL
Short Description:	This Hpt Sandwich ELISA Kit, Ready-To-Use is an in-vitro enzyme-linked immunosorbent assay for the measurement of samples in human cell culture supernatant, serum and plasma (EDTA, citrate, heparin).

Storage Instruction:	Store the unopened kit in the fridge at 2-8°C for up to 6 months. Once opened store individual kit contents according to components table provided with the kit.
Assay Time:	3 hrs

Gene Symbol:	HP
Gene ID:	3240
Uniprot ID:	HPT_HUMAN
Immunogen Region:	Ready-To-Use
Sample Type:	serum, plasma, tissue homogenates, cell lysates, cell culture supernates or other biological fluids.

Tissue Specificity	Expressed by the liver and secreted in plasma.
Post Translational Modifications
Function	As a result of hemolysis, hemoglobin is found to accumulate in the kidney and is secreted in the urine. Haptoglobin captures, and combines with free plasma hemoglobin to allow hepatic recycling of heme iron and to prevent kidney damage. Haptoglobin also acts as an antioxidant, has antibacterial activity, and plays a role in modulating many aspects of the acute phase response. Hemoglobin/haptoglobin complexes are rapidly cleared by the macrophage CD163 scavenger receptor expressed on the surface of liver Kupfer cells through an endocytic lysosomal degradation pathway. The uncleaved form of allele alpha-2 (2-2), known as zonulin, plays a role in intestinal permeability, allowing intercellular tight junction disassembly, and controlling the equilibrium between tolerance and immunity to non-self antigens.
Protein Name	Haptoglobin Zonulin Cleaved Into - Haptoglobin Alpha Chain - Haptoglobin Beta Chain
Database Links	Reactome: R-HSA-2168880 Reactome: R-HSA-6798695
Cellular Localisation	Secreted
Alternative ELISA Names	Haptoglobin ELISA kit Zonulin Cleaved Into - Haptoglobin Alpha Chain - Haptoglobin Beta Chain ELISA kit HP ELISA kit
output

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance

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