Anti-CANX antibody (543-592 aa) (STJ91978) STJ91978 上海玉博生物科技有限公司

Anti-CANX antibody (543-592 aa) (STJ91978)

简单介绍

Anti-CANX antibody (543-592 aa) (STJ91978)

产品描述

Host:	Rabbit
Applications:	WB/IHC/IF/ELISA
Reactivity:	Human/Mouse/Rat
Note:	STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description:	Rabbit polyclonal antibody anti-Calnexin (543-592 aa) is suitable for use in Western Blot, Immunohistochemistry, Immunofluorescence and ELISA research applications.

Clonality:	Polyclonal
Conjugation:	Unconjugated
Isotype:	IgG
Formulation:	Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide.
Purification:	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration:	1 mg/mL
Dilution Range:	WB 1:500-1:2000 IHC-P 1:100-300 ELISA 1:20000 IF 1:100-300
Storage Instruction:	Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.

Gene Symbol:	CANX
Gene ID:	821
Uniprot ID:	CALX_HUMAN
Immunogen Region:	543-592 aa
Specificity:	Calnexin Polyclonal Antibody detects endogenous levels of Calnexin protein.
Immunogen:	The antiserum was produced against synthesized peptide derived from the human Calnexin at the amino acid range 543-592

Function	Calcium-binding protein that interacts with newly synthesized monoglucosylated glycoproteins in the endoplasmic reticulum. It may act in assisting protein assembly and/or in the retention within the ER of unassembled protein subunits. It seems to play a major role in the quality control apparatus of the ER by the retention of incorrectly folded proteins. Associated with partial T-cell antigen receptor complexes that escape the ER of immature thymocytes, it may function as a signaling complex regulating thymocyte maturation. Additionally it may play a role in receptor-mediated endocytosis at the synapse.
Protein Name	Calnexin Ip90 Major Histocompatibility Complex Class I Antigen-Binding Protein P88 P90
Database Links	Reactome: R-HSA-168316 Reactome: R-HSA-2132295 Reactome: R-HSA-8984722 Reactome: R-HSA-901042 Reactome: R-HSA-9020956 Reactome: R-HSA-9683686 Reactome: R-HSA-9694548 Reactome: R-HSA-983170
Cellular Localisation	Endoplasmic Reticulum Membrane Single-Pass Type I Membrane Protein Endoplasmic Reticulum Melanosome Identified By Mass Spectrometry In Melanosome Fractions From Stage I To Stage Iv The Palmitoylated Form Preferentially Localizes To The Perinuclear Rough Er
Alternative Antibody Names	Anti-Calnexin antibody Anti-Ip90 antibody Anti-Major Histocompatibility Complex Class I Antigen-Binding Protein P88 antibody Anti-P90 antibody Anti-CANX antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance

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