Anti-CAPZA1 antibody (1-286) (STJ22887) STJ22887 上海玉博生物科技有限公司

Anti-CAPZA1 antibody (1-286) (STJ22887)

简单介绍

Anti-CAPZA1 antibody (1-286) (STJ22887)

产品描述

Host:	Rabbit
Applications:	WB
Reactivity:	Human/Mouse/Rat
Note:	STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description:	Rabbit polyclonal antibody anti-CAPZA1 (1-286) is suitable for use in Western Blot research applications.

Clonality:	Polyclonal
Conjugation:	Unconjugated
Isotype:	IgG
Formulation:	PBS with 0.02% Sodium Azide, 50% Glycerol, pH7.3.
Purification:	Affinity purification
Dilution Range:	WB 1:200-1:1000
Storage Instruction:	Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.

Gene Symbol:	CAPZA1
Gene ID:	829
Uniprot ID:	CAZA1_HUMAN
Immunogen Region:	1-286
Immunogen:	Recombinant fusion protein containing a sequence corresponding to amino acids 1-286 of human CAPZA1 (NP_006126.1).
Immunogen Sequence:	MADFDDRVSDEEKVRIAAKF ITHAPPGEFNEVFNDVRLLL NNDNLLREGAAHAFAQYNMD QFTPVKIEGYEDQVLITEHG DLGNSRFLDPRNKISFKFDH LRKEASDPQPEEADGGLKSW RESCDSALRAYVKDHYSNGF CTVYAKTIDGQQTIIACIES HQFQPKNFWNGRWRSEWKFT ITPPTAQVVGVLKIQVHYYE DGNVQLVSHKDVQDSLTVSN EAQTAKEFIKIIENAENEY

Function	F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments. May play a role in the formation of epithelial cell junctions. Forms, with CAPZB, the barbed end of the fast growing ends of actin filaments in the dynactin complex and stabilizes dynactin structure. The dynactin multiprotein complex activates the molecular motor dynein for ultra-processive transport along microtubules.
Protein Name	F-Actin-Capping Protein Subunit Alpha-1 Capz Alpha-1
Database Links	Reactome: R-HSA-2132295 Reactome: R-HSA-3371497 Reactome: R-HSA-6807878 Reactome: R-HSA-6811436 Reactome: R-HSA-879415 Reactome: R-HSA-8950505 Reactome: R-HSA-9662360 Reactome: R-HSA-983231
Cellular Localisation	Cytoplasm Cytoskeleton
Alternative Antibody Names	Anti-F-Actin-Capping Protein Subunit Alpha-1 antibody Anti-Capz Alpha-1 antibody Anti-CAPZA1 antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance

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