Anti-Casein Kinase 2 beta antibody (1-215) (STJ11102908) STJ11102908 上海玉博生物科技有限公司

Anti-Casein Kinase 2 beta antibody (1-215) (STJ11102908)

简单介绍

Anti-Casein Kinase 2 beta antibody (1-215) (STJ11102908)

产品描述

Host:	Rabbit
Applications:	WB/IHC
Reactivity:	Human/Mouse/Rat
Note:	STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description:	Rabbit polyclonal antibody anti-Casein Kinase 2 beta (CSNK2B) (1-215) is suitable for use in Western Blot and Immunohistochemistry research applications.

Clonality:	Polyclonal
Conjugation:	Unconjugated
Isotype:	IgG
Formulation:	PBS with 0.02% Sodium Azide, 50% Glycerol, pH7.3.
Purification:	Affinity purification
Dilution Range:	WB 1:500-1:2000 IHC-P 1:50-1:200
Storage Instruction:	Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.

Gene Symbol:	CSNK2B
Gene ID:	1460
Uniprot ID:	CSK2B_HUMAN
Immunogen Region:	1-215
Immunogen:	Recombinant fusion protein containing a sequence corresponding to amino acids 1-215 of human Casein Kinase 2 beta (Casein Kinase 2 beta (CSNK2B) ) (NP_001311.3).
Immunogen Sequence:	MSSSEEVSWISWFCGLRGNE FFCEVDEDYIQDKFNLTGLN EQVPHYRQALDMILDLEPDE ELEDNPNQSDLIEQAAEMLY GLIHARYILTNRGIAQMLEK YQQGDFGYCPRVYCENQPML PIGLSDIPGEAMVKLYCPKC MDVYTPKSSRHHHTDGAYFG TGFPHMLFMVHPEYRPKRPA NQFVPRLYGFKIHPMAYQLQ LQAASNFKSPVKTIR

Post Translational Modifications	Phosphorylated by alpha subunit.
Function	Regulatory subunit of casein kinase II/CK2. As part of the kinase complex regulates the basal catalytic activity of the alpha subunit a constitutively active serine/threonine-protein kinase that phosphorylates a large number of substrates containing acidic residues C-terminal to the phosphorylated serine or threonine. Participates in Wnt signaling. (Microbial infection) Upon infection with Epstein-Barr virus (EBV), the interaction with viral EBNA1 increases the association of CK2 with PML proteins, which increases PML phosphorylation by CK2, triggering the polyubiquitylation and degradation of PML. Seems to also suppress EBV reactivation by mediating ARK2N and JUN at the Z promoter which inhibits BZLF1 transcrition.
Protein Name	Casein Kinase Ii Subunit Beta Ck Ii Beta Phosvitin Protein G5a
Database Links	Reactome: R-HSA-1483191 Reactome: R-HSA-201688 Reactome: R-HSA-2514853 Reactome: R-HSA-445144 Reactome: R-HSA-6798695 Reactome: R-HSA-6804756 Reactome: R-HSA-6814122 Reactome: R-HSA-8934903 Reactome: R-HSA-8939243 Reactome: R-HSA-8948751 Reactome: R-HSA-9755511
Cellular Localisation	Nucleus
Alternative Antibody Names	Anti-Casein Kinase Ii Subunit Beta antibody Anti-Ck Ii Beta antibody Anti-Phosvitin antibody Anti-Protein G5a antibody Anti-CSNK2B antibody Anti-CK2N antibody Anti-G5A antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance

产品留言

标题

联系人

联系电话

内容

验证码

点击换一张

注：1.可以使用快捷键Alt+S或Ctrl+Enter发送信息!
2.如有必要,请您留下您的详细联系方式!

产品目录