Anti-CASK antibody (1-300) (STJ22891) STJ22891 上海玉博生物科技有限公司

Anti-CASK antibody (1-300) (STJ22891)

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产品名称：Anti-CASK antibody (1-300) (STJ22891)
产品型号：STJ22891
产品展商：ST john's laboratory
产品文档：无相关文档

简单介绍

Anti-CASK antibody (1-300) (STJ22891)

产品描述

Host:	Rabbit
Applications:	WB/IF
Reactivity:	Human
Note:	STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description:	Rabbit polyclonal antibody anti-CASK (1-300) is suitable for use in Western Blot and Immunofluorescence research applications.

Clonality:	Polyclonal
Conjugation:	Unconjugated
Isotype:	IgG
Formulation:	PBS with 0.02% Sodium Azide, 50% Glycerol, pH7.3.
Purification:	Affinity purification
Dilution Range:	WB 1:500-1:2000 IF/ICC 1:50-1:200
Storage Instruction:	Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.

Gene Symbol:	CASK
Gene ID:	8573
Uniprot ID:	CSKP_HUMAN
Immunogen Region:	1-300
Immunogen:	Recombinant fusion protein containing a sequence corresponding to amino acids 1-300 of human CASK (NP_001119526.1).
Immunogen Sequence:	MADDDVLFEDVYELCEVIGK GPFSVVRRCINRETGQQFAV KIVDVAKFTSSPGLSTEDLK REASICHMLKHPHIVELLET YSSDGMLYMVFEFMDGADLC FEIVKRADAGFVYSEAVASH YMRQILEALRYCHDNNIIHR DVKPHCVLLASKENSAPVKL GGFGVAIQLGESGLVAGGRV GTPHFMAPEVVKREPYGKPV DVWGCGVILFILLSGCLPFY GTKERLFEGIIKGKYKMNP

Tissue Specificity	Ubiquitous. Expression is significantly greater in brain relative to kidney, lung, and liver and in fetal brain and kidney relative to lung and liver.
Function	Multidomain scaffolding Mg(2+)-independent protein kinase that catalyzes the phosphotransfer from ATP to proteins such as NRXN1, and plays a role in synaptic transmembrane protein anchoring and ion channel trafficking. Contributes to neural development and regulation of gene expression via interaction with the transcription factor TBR1. Binds to cell-surface proteins, including amyloid precursor protein, neurexins and syndecans. May mediate a link between the extracellular matrix and the actin cytoskeleton via its interaction with syndecan and with the actin/spectrin-binding protein 4.1. Component of the LIN-10-LIN-2-LIN-7 complex, which associates with the motor protein KIF17 to transport vesicles containing N-methyl-D-aspartate (NMDA) receptor subunit NR2B along microtubules.
Protein Name	Peripheral Plasma Membrane Protein Cask Hcask Calcium/Calmodulin-Dependent Serine Protein Kinase Protein Lin-2 Homolog
Database Links	Reactome: R-HSA-212676 Reactome: R-HSA-3000170 Reactome: R-HSA-373753 Reactome: R-HSA-6794361 Reactome: R-HSA-9609736 Reactome: R-HSA-9662360 Reactome: R-HSA-9662361
Cellular Localisation	Nucleus Cytoplasm Cell Membrane Peripheral Membrane Protein
Alternative Antibody Names	Anti-Peripheral Plasma Membrane Protein Cask antibody Anti-Hcask antibody Anti-Calcium/Calmodulin-Dependent Serine Protein Kinase antibody Anti-Protein Lin-2 Homolog antibody Anti-CASK antibody Anti-LIN2 antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance

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Anti-CASK antibody (1-300) (STJ22891)